新疆汉族、维吾尔族与哈萨克族卒中后抑郁发病差异调查

发布时间：2018-11-04 20:52

【摘要】：目的调查卒中后抑郁(PSD)发病的民族差异性,为临床PSD的早期干预提供指导依据。方法以2014年1月-2015年9月间在新疆石河子大学医学院第一附属医院及新疆维吾尔自治区中医医院收治的624名脑卒中患者为研究对象。将出院后1周符合PSD诊断的分为PSD组,不符合的分为非PSD组。应用χ~2检验比较不同民族PSD发生率的差异;应用Logistic回归模型,控制社会人口学变量及疾病相关变量的影响后,分析民族对PSD发病的影响。结果 (1)汉族PSD发生率为31.2%、维吾尔族PSD发生率为19.0%、哈萨克族PSD发生率为14.2%,3个民族PSD发生率差异有统计学意义(χ~2=18.259,P=0.001)。(2)在扣除了其他因素的影响后,维吾尔族发生PSD的风险是汉族的0.392倍(OR=0.392,95%CI:0.243~0.634,P=0.001),哈萨克族发生PSD的风险是汉族的0.290倍(OR=0.290,95%CI:0.162~0.518,P=0.001)。结论相比于汉族,维吾尔族与哈萨克族是PSD的保护因素,建议未来的研究设置较长的随访期对本研究的结论进行验证。
[Abstract]:Objective to investigate the national differences of (PSD) in post-stroke depression and to provide guidance for early intervention of PSD. Methods from January 2014 to September 2015, 624 stroke patients were treated in the first affiliated Hospital of Medical College of Shihezi University of Xinjiang and Chinese Medicine Hospital of Xinjiang Uygur Autonomous region. One week after discharge, those who met PSD diagnosis were divided into PSD group and non-PSD group. 蠂 ~ 2 test was used to compare the incidence of PSD among different nationalities, and Logistic regression model was used to analyze the influence of ethnic groups on the incidence of PSD after controlling the influence of social demographic variables and disease-related variables. Results (1) the incidence of PSD in Han nationality was 31.2%, the incidence rate of PSD in Uygur nationality was 19.0, the incidence rate of PSD in Kazak nationality was 14.22.There was significant difference in the incidence of PSD among the three nationalities (蠂 ~ 2 ~ 18.259, 蠂 ~ 2 = 18.259, P < 0.01). After deducting the influence of other factors, Uygur people were 0.392 times more likely to develop PSD than the Han nationality (OR=0.392,95%CI:0.243~0.634,P=0.001). The Kazakh population is 0.290 times more OR=0.290,95%CI:0.162~0.518,P=0.001 at risk of PSD than the Han nationality. Conclusion compared with the Han nationality, Uygur and Kazak are the protective factors of PSD. It is suggested that the future study should be followed up for a longer period to verify the conclusion of this study.
【作者单位】：石河子大学医学院第一附属医院康复心理科;石河子大学医学院第一附属医院神经内科;新疆维吾尔自治区中医医院推拿科;
【基金】：院级科研项目(YL2015R0067)
【分类号】：R743.3;R749.4

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