脑干卒中患者的认知障碍研究
发布时间:2018-11-25 22:42
【摘要】:目的研究急性孤立性脑干卒中患者认知功能与正常对照之间的差异,探究脑干卒中对认知功能的影响及其主要受损的认知域。方法选取符合入组标准的、性别、年龄和受教育年限匹配的首次发病的急性孤立性脑干卒中患者29例和正常对照20例,分别进行艾登布鲁克斯认知检测(ACE-Ⅲ)、蒙特利尔认知评估量表(MoCA)、数字符号转换测验(SDMT)、韦氏数字广度测验(DS)、连线测验(TMT)、Stroop词色测验等量表评测及事件相关电位P300检测。结果脑干卒中患者MoCA量表和ACE-Ⅲ量表总体评分与对照组相比显著降低(P=0.012,P=0.004),其中受损的认知域主要为语言功能(P=0.024)及视空间功能(P=0.004)。SDMT、DS、TMT和Stroop等量表完成度欠佳,与对照组相比,均未见显著差异(P0.05)。P300检测结果显示脑干卒中患者较对照组存在显著的波幅降低(P=0.022)及潜伏期延长(P=0.033)。ACE-Ⅲ与MoCA显著正相关(P0.001),而与P300潜伏期显著负相关(P=0.006)。结论急性孤立性脑干卒中患者存在一定的认知功能障碍,受损的认知域主要为注意力、语言及视空间能力。
[Abstract]:Objective to study the difference between cognitive function and normal control in patients with acute isolated brainstem stroke, and to explore the effect of brainstem stroke on cognitive function and its main impaired cognitive domain. Methods A total of 29 patients with acute isolated brainstem stroke and 20 normal controls who matched sex, age and years of education were selected to perform ACE- 鈪,
本文编号:2357578
[Abstract]:Objective to study the difference between cognitive function and normal control in patients with acute isolated brainstem stroke, and to explore the effect of brainstem stroke on cognitive function and its main impaired cognitive domain. Methods A total of 29 patients with acute isolated brainstem stroke and 20 normal controls who matched sex, age and years of education were selected to perform ACE- 鈪,
本文编号:2357578
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