首发未治疗精神分裂症患者视觉引导眼跳中速度非对称与眼跳幅度相关性研究

发布时间：2018-12-09 11:36

【摘要】：目的探讨视觉引导眼跳中速度非对称性与眼跳幅度相关性在首发未治疗精神分裂症患者和健康者中的差异。方法选取符合ICD-10诊断标准的首发、未治疗的精神分裂症患者30例,同时选取匹配的正常对照组30例,分别进行视觉引导眼跳检查。计算眼跳的加速度非对称指数(AAI),并计算AAI与眼跳幅度的相关系数Raa。然后组间进行主序列分析,比较眼跳加速度峰值、减速度峰值等与眼跳幅度之间的一般线性关系,并进一步比较组间的Raa。结果精神分裂症组Raa值低于正常对照组(Z=-3.567,P0.01)。结论 Raa可作为精神分裂症辅助诊断的一种生物学指标。
[Abstract]:Objective to investigate the relationship between the asymmetry of speed and the amplitude of the saccade in the first episode of untreated schizophrenia and the healthy subjects. Methods Thirty patients with untreated schizophrenia who met the diagnostic criteria of ICD-10 and 30 matched normal controls were selected for visual guided eye jump examination. Calculation of the acceleration asymmetry Index (AAI), and the correlation coefficient Raa. between the AAI and the amplitude of the knuckles Then the main sequence analysis was carried out among the groups to compare the general linear relationship between the peak acceleration and deceleration peak and the amplitude of the saccade, and to compare the Raa. between the groups. Results the Raa value of schizophrenia group was lower than that of normal control group (P 0.01). Conclusion Raa can be used as a biological index for auxiliary diagnosis of schizophrenia.
【作者单位】：安徽医科大学医学心理系;安徽医科大学精神卫生临床学院安徽省精神卫生中心;深圳康宁医院暨深圳市精神卫生中心;
【基金】：安徽省自然科学基金(编号:1308085QH148)
【分类号】：R749.3

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