伴抑郁情绪内科门诊患者的血管内皮功能
发布时间:2018-12-10 08:32
【摘要】:目的:探讨内科门诊患者的抑郁情绪与血管内皮功能的关系。方法:采用横断面调查,选取就诊于三甲综合医院内科门诊,汉密顿抑郁量表17项评分≥17分和临床总体印象评分≥4分的63例患者作为伴抑郁情绪组,选取汉密顿抑郁量表17项评分7分、汉密顿焦虑量表评分≤6分、临床总体印象评分≤2分的63例患者作为无抑郁情绪组,两组年龄与体质量指数均匹配。调查患者是否存在冠心病、糖尿病、脑梗死病史,并对血糖、血脂、血压指标进行测查,采用Endo-PAT2000检测仪评估内皮功能指数(RHI)。结果:多重线性回归分析结果显示,RHI水平与伴抑郁情绪呈负向关联(β'=-0.31,P0.001)。按有/无冠心病病史分层分析伴抑郁情绪与RHI水平的关系,有冠心病病史的患者中,伴抑郁情绪者(n=28)与无抑郁情绪组(n=22)的RHI差异无统计学意义[(1.8±0.5)vs.(1.8±0.7),P0.05];无冠心病病史的患者中,伴抑郁情绪者(n=47)的RHI水平低于无抑郁情绪者(n=53)[(2.1±0.6)vs.(2.4±0.6),P0.05]。结论:内科门诊抑郁情绪患者可能存在内皮功能障碍。
[Abstract]:Objective: to investigate the relationship between depression and vascular endothelial function in outpatients. Methods: a cross-sectional survey was carried out in 63 patients with depression in the outpatient department of Department of Internal Medicine, Hamilton Depression scale (17 items 鈮,
本文编号:2370286
[Abstract]:Objective: to investigate the relationship between depression and vascular endothelial function in outpatients. Methods: a cross-sectional survey was carried out in 63 patients with depression in the outpatient department of Department of Internal Medicine, Hamilton Depression scale (17 items 鈮,
本文编号:2370286
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