强迫症患者的人格特质在早年创伤与强迫症状间的中介作用

发布时间：2018-12-29 08:04

【摘要】：目的:探讨强迫症患者中不同类型的早年创伤、人格特质与临床症状三者之间的相互作用关系,以及适应不良的人格特质在早年创伤与强迫症状间的中介作用。方法:选取147例符合精神障碍诊断与统计手册第4版(DSM-IV)诊断标准的强迫症患者,使用耶鲁-布朗强迫症状量表(Y-BOCS)测量被试的强迫症状严重度,早年创伤问卷-自评版(ETI-SF)测量其早年创伤经历,NEO大五人格量表(NEO-FFI)测量其人格特质。结果:ETI-SF中情感虐待分量表得分与Y-BOCS总分呈正相关(r=0.19,P0.05),NEO-FFI中神经质人格得分与Y-BOCS总分呈正相关(r=0.31,P0.001),宜人性人格得分与Y-BOCS总分呈负相关(r=-0.18,P0.05)。通径分析显示神经质人格在情感虐待与强迫症状间起完全中介作用,中介作用大小为0.107(95%CI:0.04~0.19,P0.05)。结论:早年情感虐待可能与强迫症状呈正相关,而神经质人格在情感虐待与强迫症状之间发挥了完全中介作用。
[Abstract]:Objective: to investigate the interaction among different types of early trauma, personality traits and clinical symptoms in patients with obsessive-compulsive disorder (OCD), and the mediating role of ill-adapted personality traits between early trauma and obsessive-compulsive symptoms. Methods: obsessive-compulsive disorder (OCD) patients who met the diagnostic criteria of the fourth edition (DSM-IV) of the Diagnostic and Statistical Manual for Mental Disorder (DSM-IV) were selected to measure the severity of obsessive-compulsive symptoms by using the Yale Brown obsessive-compulsive symptom scale (Y-BOCS). The early Trauma questionnaire (ETI-SF) was used to measure its early traumatic experience, and the NEO Big five Personality scale (NEO-FFI) was used to measure its personality traits. Results: the scores of affective abuse in ETI-SF were positively correlated with the total score of Y-BOCS (r = 0.19 P 0.05), and the scores of neurotic personality in NEO-FFI were positively correlated with the total score of Y-BOCS (r = 0.31, P 0.001). There was a negative correlation between the score of personality and the total score of Y-BOCS (r = 0.18 P 0.05). Path analysis showed that neurotic personality played a completely mediating role between affective abuse and obsessive-compulsive symptoms, and the mediating effect was 0.107 (95 CI: 0.04 0.19 P 0.05). Conclusion: emotional abuse in early years may be positively correlated with obsessive-compulsive symptoms, while neurotic personality plays a completely mediating role between affective abuse and obsessive-compulsive symptoms.
【作者单位】：上海交通大学医学院附属精神卫生中心;
【基金】：国家自然科学基金(81671340) 上海交通大学“医工交叉研究基金”(YG2013MS65) 上海市“科技创新行动计划”长三角科技联合攻关项目子项目(15495810203)
【分类号】：R749.7

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