2~3岁孤独谱系障碍儿童的脑弥散张量成像研究
发布时间:2019-04-15 19:49
【摘要】:目的:对比分析2~3岁孤独谱系障碍儿童与发育迟缓(DD)儿童的脑白质纤维结构的异常。方法:对60例符合美国精神障碍诊断和统计手册第4版(修订版)(DSM-Ⅳ-TR)诊断标准的孤独谱系障碍儿童(病例组)和35例年龄、性别、智商与之相匹配的发育障碍儿童(对照组)进行脑弥散张量成像扫描,应用基于体素的分析法比较两组全脑白质纤维结构的异常。结果:与对照组相比,孤独谱系障碍儿童胼胝体、后侧扣带、边缘叶、左侧颞下区、左侧颞中区、布罗德曼8区、右侧眶额叶下部、右侧额中区、右侧额上区等处白质各向异性值显著增大(P0.001,k≥10)。结论:与DD儿童相比,2~3岁孤独谱系障碍儿童呈现出多处脑白质纤维结构的异常,且与青少年期、成年期患者的异常形式有差异。
[Abstract]:Aim: to compare the structural abnormalities of white matter fibers between 3-year-old children with solitary pedigree disorders and (DD) children with developmental retardation. Methods: 60 children with autism pedigree disorders (DSM- 鈪,
本文编号:2458442
[Abstract]:Aim: to compare the structural abnormalities of white matter fibers between 3-year-old children with solitary pedigree disorders and (DD) children with developmental retardation. Methods: 60 children with autism pedigree disorders (DSM- 鈪,
本文编号:2458442
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