广西吸毒人群美沙酮维持治疗5年随访调查
发布时间：2019-06-15 02:12
【摘要】：目的了解广西吸毒者社区美沙酮维持治疗的变化趋势,并探讨影响保持率的相关因素。方法对2007年入组广西社区美沙酮维持治疗门诊的吸毒者进行为期5年的回顾性队列研究,采用描述性分析方法分析吸毒者人口学特征和吸毒行为,生存分析方法完成维持治疗时间及其影响因素的分析。结果共纳入研究对象2 121例,5年平均维持治疗时间为(31.1±23.8)个月,治疗时间1、1、2、3、4、≥5年者的保持率分别为25.0%、75.0%、56.9%、45.0%、34.4%、26.4%。研究对象参加治疗后1~2年内最容易退出治疗(保持率在2009年下降到45.2%),随后逐渐趋于稳定(2010—2012年保持率在31.3%~47.7%范围波动)。多因素Cox比例风险回归模型分析显示,农民(HR=1.319,P=0.001)、入组前注射吸毒(HR=1.509,P0.001)、治疗期间偷吸(HR=2.157,P=0.007)是研究对象退出治疗的危险因素,而与家人关系较好(HR=0.689,P=0.002)、生活来源于工资收入(HR=0.880,P=0.034)、MMT日均维持剂量60 mL(HR=0.817,P=0.016)是其保护因素。结论广西吸毒者社区美沙酮维持治疗保持率较低。农民、与家人关系、有工资收入、入组前注射吸毒、治疗期间偷吸及MMT日均维持剂量是吸毒者维持时间的影响因素。
[Abstract]:Objective to investigate the changing trend of methadone maintenance treatment in drug users in Guangxi and to explore the related factors affecting the retention rate. Methods A 5-year retrospective cohort study was conducted on drug users who were enrolled in the community methadone maintenance treatment clinic in Guangxi in 2007. the demographic characteristics and drug use behavior of drug users were analyzed by descriptive analysis, and the maintenance treatment time and its influencing factors were analyzed by survival analysis. Results the average duration of treatment in 5 years was (31.1 卤23.8) months, and the retention rate of patients with 5 years or more was 25.0%, 75.0%, 45.0%, 34.4% and 26.4%, respectively, and the retention rate was 25.0%, 75.0%, 45.0%, 34.4%, 26.4%, 26.4%, 25.4%, 45.0%, 34.4%, 26.4%, 26.4%, 25.0%, 45.0%, 34.4% and 26.4%, respectively. The subjects were the most likely to withdraw from the treatment within 1 to 2 years after treatment (the retention rate dropped to 45.2% in 2009), and then gradually stabilized (the retention rate fluctuated in the range of 31.3% and 47.7% from 2010 to 2012). Multivariate Cox proportional risk regression model analysis showed that farmers (HR=1.319,P=0.001), injecting drug use (HR=1.509,P0.001) and stealing during treatment (HR=2.157,P=0.007) were the risk factors for the subjects to withdraw from the treatment, but had a good relationship with their families (HR=0.689,P=0.002). Life came from wage income (average daily maintenance dose of 60 mL (HR=0.817,). P 鈮，
本文编号：2499884
[Abstract]:Objective to investigate the changing trend of methadone maintenance treatment in drug users in Guangxi and to explore the related factors affecting the retention rate. Methods A 5-year retrospective cohort study was conducted on drug users who were enrolled in the community methadone maintenance treatment clinic in Guangxi in 2007. the demographic characteristics and drug use behavior of drug users were analyzed by descriptive analysis, and the maintenance treatment time and its influencing factors were analyzed by survival analysis. Results the average duration of treatment in 5 years was (31.1 卤23.8) months, and the retention rate of patients with 5 years or more was 25.0%, 75.0%, 45.0%, 34.4% and 26.4%, respectively, and the retention rate was 25.0%, 75.0%, 45.0%, 34.4%, 26.4%, 26.4%, 25.4%, 45.0%, 34.4%, 26.4%, 26.4%, 25.0%, 45.0%, 34.4% and 26.4%, respectively. The subjects were the most likely to withdraw from the treatment within 1 to 2 years after treatment (the retention rate dropped to 45.2% in 2009), and then gradually stabilized (the retention rate fluctuated in the range of 31.3% and 47.7% from 2010 to 2012). Multivariate Cox proportional risk regression model analysis showed that farmers (HR=1.319,P=0.001), injecting drug use (HR=1.509,P0.001) and stealing during treatment (HR=2.157,P=0.007) were the risk factors for the subjects to withdraw from the treatment, but had a good relationship with their families (HR=0.689,P=0.002). Life came from wage income (average daily maintenance dose of 60 mL (HR=0.817,). P 鈮，
本文编号：2499884
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