恢复期老年期抑郁症患者认知功能与日常生活能力相关性研究

发布时间：2019-06-20 04:31

【摘要】：目的 :研究恢复期老年期抑郁症(remitted geriatric depression,RGD)患者认知功能和日常生活能力以及两者的相关性。方法:入组RGD患者51例,正常对照组52例,主要以Mattis痴呆评定量表(Mattis dementia rating scale,MDRS)和日常生活能力评估量表(activities of daily living scal,ADL)评估受试者认知功能及日常生活能力。结果:RGD患者认知功能明显低于对照组,且其认知功能与汉密尔顿抑郁量表(Hamilton depression rating scale,HAMD)得分和是否服用抗抑郁药无相关性;RGD患者ADL评分显著低于正常对照组;MDRS量表起始/保持得分与ADL评分存在显著负相关。结论:认知功能障碍可能作为RGD患者内源性损害持续存在,并影响患者日常生活能力。
[Abstract]:Objective: to study the cognitive function and daily living ability of convalescent elderly patients with depression (remitted geriatric depression,RGD) and the correlation between them. Methods: 51 patients with RGD and 52 patients with normal control group were enrolled in this study. Mattis dementia rating scale (Mattis dementia rating scale,MDRS) and ability of daily living (activities of daily living scal,ADL) were used to evaluate the cognitive function and daily living ability of the subjects. Results: the cognitive function of RGD patients was significantly lower than that of the control group, and there was no correlation between the cognitive function and the score of Hamilton depression scale (Hamilton depression rating scale,HAMD) and whether or not to take antidepressants. The ADL score of RGD patients was significantly lower than that of the normal control group. There was a significant negative correlation between the starting / maintaining score of MDRS scale and the ADL score. Conclusion: cognitive impairment may persist as an intrinsic impairment in patients with RGD and affect the ability of daily living of patients.
【作者单位】：南京医科大学附属脑科医院老年精神科;东南大学附属中大医院神经精神医学科;
【基金】：国家临床重点专科建设项目(卫生部医政司2011-873) 江苏省医学重点学科(江苏省卫生厅2011-12) 国家自然科学基金重大研究计划培育项目(91132727) 南京市医学科技发展项目(YKK13126)
【分类号】：R749.4

【共引文献】