老年科住院患者抗抑郁药物应用77例分析

发布时间：2019-07-11 08:10

【摘要】：目的探讨老年人应用抗抑郁药的安全性,为老年人合理使用抗抑郁药提供参考。方法回顾性分析2012年1月至2013年12月北京协和医院院老年示范病房77例65岁以上患者的抗抑郁药物的使用情况、起始剂量及不良反应。结果经老年医学跨学科团队会诊,77例均服用新型抗抑郁药,其中舍曲林使用率最高,对低体重指数患者更多选择米氮平治疗,伴有慢性疼痛的患者中50%使用5-羟色胺和(或)去甲肾上腺素再摄取抑制剂。70例住院后开始抗抑郁药治疗,72.8%的患者初始给药量从小剂量开始,不良反应发生率为8.6%(6/70)。结论应结合老年患者特点,以及抗抑郁药的特点、不良反应和药物之间的相互作用来选择适当的抗抑郁药物。
[Abstract]:Objective to explore the safety of antidepressants in the elderly and to provide reference for the rational use of antidepressants in the elderly. Methods from January 2012 to December 2013, the use, initial dose and adverse reactions of antidepressants in 77 patients over 65 years old in the demonstration ward of Peking Union Medical College Hospital were analyzed retrospectively. Results after interdisciplinary team consultation of geriatrics, 77 cases were treated with new antidepressants, among which sertralin was the most frequently used. 50% of patients with chronic pain were treated with sertraline and / or norepinephrine reuptake inhibitor. 70 patients began antidepressant treatment after hospitalization, and 72.8% of patients began to take antidepressants at a low dose. The incidence of adverse reactions was 8.6% (6 鈮，

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