咪达唑仑治疗口腔恐惧症的不良反应

发布时间：2018-01-13 22:00

本文关键词：咪达唑仑治疗口腔恐惧症的不良反应　出处：《国际口腔医学杂志》2016年01期 　论文类型：期刊论文

【摘要】：口腔恐惧症系指一组与口腔诊疗相关的异常心理、生理和行为状态,其临床表现为患者心跳加快、血压异常、出汗、多语、肌肉紧张、面色苍白乃至晕厥等。咪达唑仑具有抗焦虑、镇静、催眠、抗惊厥和肌肉松弛作用,服用后患者可产生短暂的顺行性记忆缺失,不能回忆起在药物高峰期间所发生的事情。咪达唑仑常见的轻微不良反应包括打嗝、恶心、呕吐、头疼、眩晕、尿床、幻觉、头晕、复视以及唾液分泌过多、行为异常和短暂的血氧饱和度下降等,严重的不良反应包括心脏骤停、心率改变、变态反应、血栓形成、喉头痉挛和支气管痉挛以及呼吸抑制和呼吸停止等。目前越来越多的口腔恐惧症人群接受咪达唑仑镇静,而施术者水平参差不齐,因此有必要对其不良后果进行追踪并建立其相关不良后果数据库,建立一个通用的咪达唑仑不良反应标准,以提高口腔镇静技术的安全性,给予临床应用其镇静时以指导。
[Abstract]:Oral phobia refers to a group of oral diagnosis and treatment related to abnormal psychological, physiological and behavioral state, its clinical manifestations for patients with rapid heart rate, abnormal blood pressure, sweating, multilingual, muscle tension. Midazolam has anti-anxiety, sedation, hypnosis, anticonvulsion and muscle relaxation effects, and can produce transient antegrade memory loss after taking midazolam. It is not possible to recall what happened during the drug rush. Mild adverse effects of midazolam include hiccups, nausea, vomiting, headache, dizziness, bed wetting, hallucinations, dizziness, diplopia, and excessive saliva secretion. Behavioral abnormalities and a brief decline in oxygen saturation. Severe adverse effects include cardiac arrest, heart rate changes, allergies, and thrombosis. Laryngospasm and bronchospasm, as well as respiratory depression and apnea, etc. At present, more and more people with oral phobia receive midazolam sedation with varying levels of operation. Therefore, it is necessary to track its adverse effects and establish its related adverse consequences database, and establish a general adverse reaction standard of midazolam, in order to improve the safety of oral sedation. To give clinical application of its sedation to guide.
【作者单位】：济宁市第一人民医院口腔科;
【基金】：济宁市医学计划(2013jnwk111)~~
【分类号】：R782.054
【正文快照】： 目前,口腔恐惧症仍然是口腔疾病治疗中的一大难题。在复杂的口腔恐惧症治疗过程中,单纯的局部麻醉往往难以难以消除口腔恐惧症,尤其是儿童以及伴有心血管疾病的老人和不能配合医师治疗的智障人士等。全身麻醉虽然可以消除口腔恐惧症,但其往往会伴随大的并发症而且花费较多[1]

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