钛网应用于即刻种植骨缺损骨再生的实验研究

发布时间：2018-02-19 17:41

本文关键词： 钛网即刻种植垂直-水平联合型骨缺损引导骨组织再生技术　出处：《安徽医科大学学报》2017年06期 　论文类型：期刊论文

【摘要】：目的通过动物实验观察钛网联合引导骨组织再生技术(GBR)在不同植体即刻种植周围骨缺损骨再生过程中的实际成骨效果。方法 6只成年健康比格犬,拔除双侧下颌2、3、4前磨牙,一侧植入韩国DIO植体4枚,另一侧植入ITI植体4枚。每颗植体周围制作垂直-水平联合型骨缺损,48枚植体按照处理方法不同分为4组:对照组、GBR组、钛网+骨粉组、钛网+GBR组。6个月后处死实验犬,通过直观测量、硬组织切片和新生骨形成率比较各组骨再生效果。结果酸蚀喷砂(SLA)表面的植体周围骨再生各项指标均明显优于可吸收研磨介质(RBM)表面;组间相比差异均有统计学意义(P0.05),钛网+GBR组骨再生效果最佳,GBR组和钛网+骨粉组次之,对照组最差,其中GBR组和钛网+骨粉组差异无统计学意义。结论 SLA表面处理方法有利于即刻种植周围骨缺损的骨整合;钛网联合GBR技术作为一种即刻种植周围骨缺损骨再生的新方法,效果稳定可靠。
[Abstract]:Objective to observe the actual osteogenic effect of titanium mesh combined with guided bone tissue regeneration (GBR) in bone regeneration process of bone defects immediately implanted in different implants. Methods six adult healthy Beagle dogs were used to remove the bilateral mandibular premolars. Four Korea DIO implants were implanted on one side and four ITI implants were implanted on the other side. 48 vertical and horizontal bone defect implants were made around each implant and divided into 4 groups according to the treatment methods: control group, titanium mesh bone powder group. After 6 months, the dogs were killed and the dogs were measured intuitively. Results the indexes of bone regeneration on the surface of SLAs were superior to those of the absorbable grinding media (RBM). The difference between the two groups was statistically significant (P 0.05). The best bone regeneration effect was found in the titanium mesh GBR group and the titanium mesh bone powder group, and the control group was the worst. There was no significant difference between the GBR group and the titanium mesh bone powder group. Conclusion the SLA surface treatment is beneficial to the bone integration of the immediate peri-implant bone defect, and the titanium mesh combined with GBR technique is a new method for bone regeneration of the immediate peri-implant bone defect. The effect is stable and reliable.
【作者单位】：安徽医科大学解放军八一临床学院口腔科;
【基金】：2014年度南京军区医学科技创新课题面上项目(编号:14MS045)
【分类号】：R783.6

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