陈渭良伤科油干预治疗复发性口腔溃疡的效果

发布时间：2018-02-27 11:05

本文关键词： 陈渭良伤科油复发性口腔溃疡白细胞介素-　出处：《广东医学》2017年14期 　论文类型：期刊论文

【摘要】：目的探讨陈渭良伤科油干预治疗复发性口腔溃疡(ROU)的临床疗效。方法选取80例热毒炽盛证ROU患者,随机分为2组,对照组给予口服维生素B2、维生素C、醋酸泼尼松片,观察组在对照组基础上加用陈渭良伤科油局部外涂,治疗周期为7 d。比较两组间溃疡大小、充血程度、疼痛程度积分、血清白细胞介素-2(IL-2)水平、临床疗效之间的差异。结果治疗后观察组的溃疡大小、充血程度、疼痛程度积分明显低于对照组,观察组的血清IL-2水平高于对照组,差异均有统计学意义(P0.05)。观察组近期疗效优于对照组(P0.05),而两组的远期复发率差异无统计学意义(P0.05)。结论陈渭良伤科油治疗ROU虽不能降低ROU的远期复发率,但近期疗效明显优于单纯西药治疗,能显著改善患者疼痛的程度,加速溃疡愈合,可能与促进外周血IL-2的分泌有关。
[Abstract]:Objective to investigate the clinical effect of Chen Weiliang's oil intervention in the treatment of recurrent oral ulcer. Methods 80 cases of ROU with heat toxin and incandescent syndrome were randomly divided into two groups. The control group was given orally vitamin B2, vitamin C and prednisone acetate. The treatment period was 7 days. The size of ulcer, the degree of hyperemia, the score of pain degree and the level of serum interleukin-2 (IL-2) were compared between the two groups. Results the size of ulcer, the degree of congestion and the score of pain degree in the observation group were significantly lower than those in the control group, and the serum IL-2 level in the observation group was higher than that in the control group. The short-term curative effect in the observation group was better than that in the control group (P 0.05), but there was no significant difference in the long-term recurrence rate between the two groups. Conclusion the long term recurrence rate of ROU can not be reduced in the treatment of ROU with Chen Weiliang Trauma Oil, and there is no significant difference in the long term recurrence rate between the two groups. But the short-term curative effect was obviously better than that of western medicine alone, which could significantly improve the degree of pain and accelerate the healing of ulcer, which may be related to the promotion of IL-2 secretion in peripheral blood.
【作者单位】：广州中医药大学附属佛山中医院口腔医疗中心;广州中医药大学附属佛山中医院心血管内科;
【基金】：佛山市省级医学重点专科培育项目(编号:Fspy3-2015018)
【分类号】：R781.5

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