口腔颌面部多间隙感染患者住院期间不良结局发生的危险因素分析

发布时间：2018-03-02 21:43

本文选题：感染　切入点：预后　出处：《中国全科医学》2017年S1期 　论文类型：期刊论文

【摘要】：目的探讨口腔颌面部多间隙感染患者住院期间不良结局发生的危险因素,为临床治疗、改善患者的预后提供参考。方法回顾性收集2000年2月—2015年2月在浙江省宁波市第二医院收治的口腔颌面部多间隙感染患者181例的临床资料,收集患者的感染病因及一般临床资料,按照住院期间是否出现不良结局分为两组:结局不良组(n=42)和结局良好组(n=139),比较两组患者一般临床资料、实验室检查指标差异,并利用Logistic回归分析探讨口腔颌面部多间隙感染患者住院期间不良结局的危险因素。结果 181例患者中有42例住院期间出现不良结局(发生率23.2%);其中以牙源性最常见。单因素分析提示两组患者在年龄、合并基础病、受累间隙数量、入院时血红蛋白、血清清蛋白、超敏C反应蛋白(hs-CRP)、入院时血糖水平、白细胞计数(WBC)、中性粒细胞分数(PMN),差异有统计学意义(P0.05)。口腔颌面部多间隙感染患者住院期间不良结局发生的多因素Logistic回归分析最终筛选出年龄、合并基础病、受累间隙数量、hs-CRP、入院血糖水平是患者住院期间不良结局独立危险因素,而血清清蛋白是保护性因素。结论口腔颌面部多间隙感染患者住院期间不良结局的发生受到多种因素的影响,与年龄、受累间隙数量、合并基础病、hs-CRP、血糖及血清清蛋白等密切相关,临床中应当重视此类高危因素。
[Abstract]:Objective to investigate the oral and maxillofacial space infection risk factors for adverse outcomes of patients, to provide reference for the clinical treatment, improve the prognosis of the patients. Methods from February 2000 to February 2015 in the clinical data of 181 patients admitted to Zhejiang province Ningbo City Second Hospital of oral and maxillofacial space infection more infection, etiology and clinical data collect the patients during hospitalization, according to whether the adverse outcomes were divided into two groups: poor outcome group (n=42) and good outcome group (n=139), compared two groups of patients with clinical data, laboratory examination and difference index, using Logistic regression analysis to explore the oral maxillofacial space infection risk factors during adverse outcomes in hospitalized patients. Results in 181 cases of adverse outcome occurred in 42 patients during hospitalization (23.2%); the most common odontogenic. Single factor analysis showed that two group In the age of patients, with basic diseases, the involvement of clearance number, admission hemoglobin, serum albumin, high sensitive C reactive protein (hs-CRP), admission blood glucose level, white blood cell count (WBC), neutrophil fraction (PMN), the difference was statistically significant (P0.05). Oral and maxillofacial space infection in hospitalized patients multivariate Logistic regression analysis of adverse outcomes occurred during the final screening age, underlying disease, involvement of clearance number, hs-CRP, admission blood glucose level during the adverse outcomes of independent risk factors of hospitalized patients, and serum albumin is a protective factor. Conclusion oral and maxillofacial space infection more adverse outcomes occurred during hospitalization were affected by a variety of the age of the patients and the factors involved, the number of the gaps, with basic diseases, hs-CRP, blood glucose and serum albumin is closely related to clinical attention should be paid to such risk factors.

【作者单位】：浙江省宁波市第二医院;
【分类号】：R782.3

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