不同引发剂对联苯牙科树脂性能的影响

发布时间：2018-03-07 06:16

本文选题：复合树脂　切入点：引发剂　出处：《吉林大学》2017年硕士论文　论文类型：学位论文

【摘要】：由有机树脂基质、引发剂体系和无机填料组成的牙科复合树脂是一种广泛用于口腔临床的充填材料,以双酚A-双甲基丙烯酸缩水甘油酯(Bisphenol A-glycidyl methacrylate,Bis-GMA)作为树脂基质单体的牙科复合树脂充填材料是牙体缺损充填治疗的首选材料。由于牙科复合树脂充填材料具有良好的粘结性能,它可以保留更多的牙体组织,满足患者对美观的要求;但是它在口腔环境中使用一段时间后会出现各种问题,其中发生率最大的是牙体组织继发龋以及充填材料出现磨损折断,主要原因为充填材料的聚合收缩及其与牙体组织的机械性能不匹配,因此,研究者不断研究开发新材料以期替代当前树脂[1,2],低收缩高机械性能的复合树脂的研制成为当前研究热点,对当前广泛应用的树脂单体BisGMA的改性以及合成新型树脂单体是研究方向之一。本课题组在前期设计合成了一种新型丙烯酸酯类牙科树脂基质单体--3,3′,5,5′-四甲基联苯二酚型环氧丙烯酸酯(TMBPEA),单体结构的联苯结构提高了聚合物的刚性,且减小在聚合过程中得空间构象变化。该研究以Bis-GMA单体作为对照组,发现以TMBPEA单体为基质的树脂基质体系固化后聚合收缩小,而且抗弯强度高,但二者双键转化率在统计学上无显著性差异。双键转化率的大小与树脂材料的性能密切相关,转化率较高的材料交联密度大,内部结构更加紧凑,可以提高机械性能,且材料不易变色,同时将提高材料的硬度,耐磨性和生物安全性。聚合双键转化率影响因素:单体、引发剂、固化方式及时间,在这三种因素中引发剂的种类及含量是至关重要的,引发剂在接收适当光波范围内的光照下能够直接使树脂从黏性液态体系转变为固态,转变的速率及程度均与引发剂有直接关系,因此,本研究将引入一种新的引发剂PPD,探讨不同引发剂对以TMBPEA为单体的树脂基质共聚体系双键转化率的影响,以期通过新型引发剂提高该体系的双键转化率,从而进一步提高材料的力学性能。实验方法:将单体(TMBPEA)、稀释剂(双甲基丙烯酸二缩三乙二醇酯TEGDMA)、引发剂、助引发剂混合均匀形成树脂基质体系,共聚体系中单体与稀释剂的比例是7:3,引发剂与助引发剂比例为1:1;实验根据引发剂不同成分和比例分组:PPD组:以1%的PPD为引发剂;PPD+CQ组:按照CQ:PPD质量比1:1联合应用作为引发剂;对照组:以1%的CQ为引发剂。分别测定三组样品的双键转化率、聚合收缩和机械性能(参照牙科行业相关标准)。结果:PPD组聚合转化率、机械性能均优于CQ体系,而PPD+CQ组复合树脂体系聚合转化率、聚合收缩、机械性能均优于CQ体系,PPD+CQ组复合树脂体系与PPD相比虽然机械性能无统计学差异,但是聚合转化率、聚合收缩性能均优于PPD体系(p0.05)。结论:PPD是一种性能较理想的引发剂,且PPD与CQ联合应用能够协同提高树脂基质体系的双键转化率,又进一步提高了树脂的各种性能,具有良好的临床应用前景。
[Abstract]:The organic resin matrix, causing dental composite resin and inorganic filler agent system is a widely used dental filling materials, with bisphenol A- bis glycidyl methacrylate (Bisphenol A-glycidyl, methacrylate, Bis-GMA) as a dental composite resin filling material matrix resin monomer is the preferred material for filling tooth defect because of dental composite resin filling material has good bonding properties, it can retain the teeth more, meet the aesthetic requirements of patients; but it is used for a period of time in the oral environment after the emergence of various problems, which is the largest incidence of wear broken tooth caries and filling materials, mainly the reason for the polymerization shrinkage of filling materials and the mechanical properties of dental tissues do not match, therefore, researchers continue to research and development of new materials to replace the The development of composite resin [1,2] resin with high mechanical properties and low shrinkage has become a hotspot of current research, the resin monomer BisGMA is widely used in the modification and synthesis of novel resin monomer is one of the research directions of the research group. A new type of acrylic dental resin matrix monomer --3,3 'synthesis in the design stage, 5,5 four' - methyl biphenol epoxy acrylate (TMBPEA), biphenyl monomer structure improves the rigidity of the polymers, and reduce the space conformation changes during the polymerization process. The research is based on the Bis-GMA monomer as the control group, the TMBPEA monomer for curing resin matrix system matrix after polymerization shrinkage, but the bending strength is high, but the two double bond conversion, there were no statistically significant differences in size. Performance is closely related with the resin material double bond conversion rate, conversion rate higher crosslinking density is large, The internal structure is more compact, can improve the mechanical properties, and the material is not easy to change, at the same time will increase the hardness, wear resistance and biocompatibility. Double bond polymerization conversion factors: monomer, initiator and curing time in these three factors lead to the type and content of agent is crucial. The resin can directly trigger from viscous liquid system into solid agent in receiving appropriate light within the scope of the light, the rate and extent of change and the initiator has a direct relationship, therefore, this study will introduce a new initiator PPD, to investigate the different influence of initiators on TMBPEA resin matrix copolymerization system double bond monomer conversion rate, in order to improve the system of the new initiator of the double bond conversion rate, so as to further improve the mechanical properties of materials. Methods: monomer (TMBPEA), diluent (double methacrylic acid two shrink Triethylene glycol ester TEGDMA), initiator, CO initiator mixture forming resin matrix system, 7:3 is a monomer in the copolymerization system and diluent ratio, initiator and initiator ratio of 1:1; experiment according to the initiator of different composition and proportion of group: PPD group with 1% PPD as initiator; PPD+CQ group according to the mass ratio of CQ:PPD 1:1 combined application as initiator; control group: 1% CQ as initiator. Three groups of samples were measured by double bond conversion, polymerization shrinkage and mechanical properties (refer to the dental industry standards). Results: in group PPD, polymerization conversion, mechanical properties are better than that of CQ system, and the PPD+CQ group composite resin polymerization conversion rate, polymerization shrinkage, mechanical properties are better than that of CQ system, PPD+CQ group compared with PPD composite resin system although the mechanical properties of no significant difference, but the conversion rate, polymerization shrinkage properties are better than the PPD system (P0.05). Conclusion: PPD An ideal initiator is available. Combined application of PPD and CQ can improve the double bond transformation rate of resin matrix system, and further improve various properties of resin, so it has good clinical application prospect.

【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R783.1

【相似文献】