有机硅季铵盐浸泡纯钛对白假丝酵母菌生长的抑制作用

发布时间：2018-03-13 06:06

本文选题：有机硅季铵盐　切入点：纯钛　出处：《国际口腔医学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的通过有机硅季铵盐溶液浸泡处理纯钛试件,研究该方法对白假丝酵母菌的抗菌效果。方法制作纯钛试件,将其随机分为A~F的6组,A~E组分别用浓度为1%、5%、10%、30%、60%的有机硅季铵盐溶液对纯钛试件进行抗菌处理,F组用蒸馏水浸泡处理作为对照,每组再分4小组,各小组处理时间分别为30、60、120、240 min,用比浊法统计分析有机硅处理后的纯钛试件对白假丝酵母菌生长的影响。将试件分别进行0、2 500、5 000、10 000次的冷热循环实验后再进行细菌培养,检验有机硅季铵盐是否具有长效抗菌性。结果不同处理浓度对白假丝酵母菌生长有影响;不同处理时间对白假丝酵母菌生长无影响;处理浓度和处理时间两因素之间存在交互作用。1%的有机硅季铵盐浸泡纯钛即可使其产生抗菌性,浸泡120 min抗菌效果最佳。冷热循环5 000次后纯钛仍具有抗菌性;10 000次后无抗菌性。结论有机硅季铵盐溶液浸泡纯钛,对白假丝酵母菌生长具有抑制作用,可使纯钛具有长效抗菌性能。
[Abstract]:Objective to study the antibacterial effect of this method against Candida albicans by soaking the pure titanium specimen in organosilicon quaternary ammonium salt solution. They were randomly divided into 6 groups of Agna F, group A and group E, which were treated with 10% organic silicon quaternary ammonium salt solution for antibacterial treatment of pure titanium samples. Group F was treated with distilled water as control group, and each group was divided into 4 groups, and each group was divided into 4 groups, and each group was divided into 4 groups, each group was divided into 4 groups, and the control group was treated with organic silicon quaternary ammonium salt solution for antimicrobial treatment. The treatment time of each group was 30 ~ 60 ~ 120 ~ 240 min. The effect of pure titanium sample treated with organosilicon on the growth of Candida albicans was statistically analyzed by turbidimetric method. Results the growth of Candida albicans was affected by different concentration of organic silicon quaternary ammonium salt, and the growth of Candida albicans was not affected by different treatment time. There was interaction between treatment concentration and treatment time. 1% organic silicon quaternary ammonium salt soaking pure titanium could produce antimicrobial activity. The antibacterial activity of pure titanium was best after immersion for 120 min. The pure titanium still had antibacterial activity after 5 000 cycles. Conclusion soaking pure titanium in organosilicon quaternary ammonium salt solution can inhibit the growth of Candida albicans. It can make pure titanium have long effect antibacterial property.
【作者单位】：河北医科大学第二医院口腔修复科;石家庄医学高等专科学校口腔系;
【基金】：河北省卫生与计划生育委员会重点科技研究计划(JL2014-0006)~~
【分类号】：R783.1

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