老年2型糖尿病与糖调节受损患者和正常人群口腔假丝酵母菌属感染的比较

发布时间：2018-03-22 10:07

本文选题：型糖尿病　切入点：糖调节受损　出处：《中华医院感染学杂志》2014年12期 　论文类型：期刊论文

【摘要】：目的研究老年2型糖尿病与糖调节受损及正常人群的口腔假丝酵母菌属感染,以降低感染率。方法选择2009年1月-2013年7月150例老年2型糖尿病患者、150例糖调节受损患者及150名正常人群进行研究,检测分析3组受试者假丝酵母菌属阳性率、感染率及携带率,并对其唾液流量、pH值及空腹血糖值进行记录,采用SPSS18.0统计软件进行数据处理。结果老年2型糖尿病患者假丝酵母菌属阳性率、感染率分别为24.00%、8.66%,高于糖调节受损患者的9.33%、2.66%,也明显高于正常人群的7.33%、2.66%,3组数据比较差异有统计学意义(P0.05);假丝酵母菌属携带率3组比较差异均无统计学意义;老年2型糖尿病和糖调节受损患者的唾液流量及pH值均明显低于正常对照组,但空腹血糖值均明显高于正常组,差异均有统计学意义(P0.01)。结论老年2型糖尿病患者比糖调节受损及正常人群易发生口腔假丝酵母菌属感染;年龄、有无义齿、空腹血糖值是口腔假丝酵母菌属感染的危险因素。
[Abstract]:Objective to study the oral Candida infection in the elderly with type 2 diabetes mellitus and impaired glucose regulation and normal population. Methods 150 patients with impaired glucose regulation and 150 normal controls were selected from January 2009 to July 2013 to study the positive rate of Candida cerevisiae in three groups of subjects. The infection rate and carrying rate were recorded and the salivary flow pH value and fasting blood glucose value were recorded. The data were processed by SPSS18.0 software. Results the positive rate of Candida in the elderly patients with type 2 diabetes mellitus was positive. The infection rate was 24.00 and 8.66, respectively, which was higher than 9.33 and 2.66 in the patients with impaired glucose regulation, and also significantly higher than that in the normal group of 7.33 and 2.66. There were significant differences among the three groups (P 0.05), but there was no significant difference in the carrying rate of Candida among the three groups. The saliva flow and pH value in the elderly patients with type 2 diabetes mellitus and impaired glucose regulation were significantly lower than those in the normal control group, but the fasting blood glucose levels were significantly higher than those in the normal control group. Conclusion elderly patients with type 2 diabetes are more susceptible to oral candida infection than those with impaired glucose regulation, age, denture and fasting blood glucose are the risk factors of oral Candida spp infection.
【作者单位】：重庆市红十字会医院(江北区人民医院)口腔科;重庆市江北区中医院口腔科;
【基金】：国家自然科学基金资助项目(81000458)
【分类号】：R587.1;R781.5

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