奥硝唑羧甲基壳聚糖联合透明质酸辅助牙周基础治疗老年慢性牙周炎效果观察

发布时间：2018-03-23 03:15

本文选题：奥硝唑羧甲基壳聚糖　切入点：透明质酸　出处：《山东医药》2017年34期 　论文类型：期刊论文

【摘要】：目的观察奥硝唑羧甲基壳聚糖联合透明质酸辅助牙周基础治疗老年慢性牙周炎的效果。方法将120例老年慢性牙周炎患者随机分为两组各60例,均行牙周基础治疗;术后对照组从牙周袋底部注入透明质酸,观察组注入奥硝唑羧甲基壳聚糖联合透明质酸,每周复诊放药1次,共4次。治疗后评价两组临床疗效,治疗前后检查菌斑指数(PLI)、出血指数(BI)、探针深度(PD)、附着丧失(AL),采集龈下菌斑并用光学显微镜观察螺旋体所占百分比(S%),采用苯甲酰精氨酸萘酰胺试验检测龈下菌斑胰蛋白酶样酶(TLE)。结果观察组总有效率为93.33%,高于对照组的78.33%(P0.05)。治疗前两组PLI、PD、AL、BI及S%、TLE比较,差异无统计学意义(P均0.05);治疗后两组PLI、PD、AL、BI及S%、TLE均下降,观察组PLI、PD、AL、BI及S%、TLE均低于对照组(P均0.05)。结论奥硝唑羧甲基壳聚糖联合透明质酸辅助牙周基础治疗老年慢性牙周炎疗效较好,可明显改善患者牙周相关指标,降低龈下菌斑螺旋体数量及TLE水平。
[Abstract]:Objective to observe the effect of ornidazole carboxymethyl chitosan combined with hyaluronic acid in the treatment of chronic periodontitis in elderly patients. The control group was injected with hyaluronic acid from the bottom of the periodontal bag, and the observation group was injected with ornidazole carboxymethyl chitosan combined with hyaluronic acid. Before and after treatment, plaque index (PLI), bleeding index (BI), probe depth (PDD), attachment loss (ALP), subgingival plaque were collected and observed by optical microscope. Subgingival plaque was detected by benzoyl arginine naphthalamide test. Results the total effective rate of the observation group was 93.33, which was higher than that of the control group (78.33%, P 0.05). There was no significant difference between the two groups (P < 0.05), and after treatment, the levels of PLII-PD-ALBI and Schi-TLE in the two groups were decreased, and the levels of PLII-PD-ALBI and SG-TLE in the observation group were lower than those in the control group (P < 0.05). Conclusion Ornidazole carboxymethyl chitosan combined with hyaluronic acid in the treatment of periodontal periodontitis in the elderly is better than that in the control group. It can obviously improve the periodontal index and reduce the number of subgingival plaque spirochetes and the level of TLE.
【作者单位】：中国人民解放军第254医院;天津市口腔医院;
【分类号】：R781.42

【相似文献】