某电解铝厂周边居民尿氟水平及儿童氟斑牙患病状况

发布时间：2018-03-23 18:28

本文选题：氟　切入点：尿氟　出处：《环境与职业医学》2015年06期

【摘要】：[目的]观察某电解铝厂周边居民的尿氟水平与每日摄氟量之间的关系,并探讨儿童氟斑牙与累计摄氟量之间的剂量效应关系。[方法]于2013年7月选择广西某电解铝厂周边0.3 km,1.3 km处分别选择3个和2个自然屯作为监测点1和2,于铝厂3.5 km处的1个自然屯作为对照点(监测点3)。于各监测点分别随机抽取50名以上当地出生、生活且无职业氟暴露史的居民(共计388人)作为调查对象。问卷调查膳食摄入量;收集其晨尿检测尿氟;对所有6~12岁儿童由专科医生进行氟斑牙检查;对各监测点空气、居民饮用水、农作物、蔬菜和肉类中的氟含量进行检测,评估儿童累计摄氟量与儿童氟斑牙患病率之间的关系。[结果]监测点1和2及对照点居民每日摄氟量分别为(0.73±0.13)、(0.70±0.11)、(0.39±0.03)mg/d,差异有统计学意义(P0.05);上述3组人群尿氟浓度分别为(1.80±0.84)、(1.44±0.86)、(0.71±0.39)mg/L,差异有统计学意义(P0.05);偏相关分析在控制年龄因素后,人群尿氟浓度与每日摄氟量相关系数r=0.441(P0.05);在儿童累计摄氟量与儿童氟斑牙患病率的剂量效应关系研究中,计算出儿童累计摄氟量的基准剂量(BMD)和基准剂量95%可信区间下限(BMDL)分别为1 371.11 mg和572.98 mg。[结论]该电解铝厂周边居民尿氟浓度及儿童氟斑牙发病率均增高,可能与该厂排放污染物有关。
[Abstract]:[objective] to observe the relationship between urinary fluorine level and daily fluorine intake of residents around an electrolytic aluminum factory. The dose-effect relationship between children's dental fluorosis and cumulative fluoride intake was investigated. [methods] in July 2013, 3 and 2 natural sites were selected as monitoring sites at 1.3 km around an electrolytic aluminum factory in Guangxi, and 1 and 2 in aluminium factory. A natural village at 3.5 km was used as a control point (monitoring site 3). More than 50 local births were randomly selected from each monitoring site. A total of 388 residents (388 persons in total) who lived without a history of occupational fluoride exposure were investigated. Dietary intake was surveyed; morning urine was collected for urine fluorine testing; dental fluorosis was performed on all 612 year old children by a specialist; air at all monitoring points was examined. Fluorine levels in drinking water, crops, vegetables and meat were tested. To evaluate the relationship between the cumulative fluoride intake of children and the prevalence rate of dental fluorosis in children. [results] the daily fluoride intake of the residents in the monitoring sites 1 and 2 and the control points were 0.73 卤0.13% 0.70 卤0.11 mg / d, respectively. The difference was statistically significant (P 0.05), and the urinary fluorine concentrations in the above three groups were respectively 0.73 卤0.13 mg / d and 0.39 卤0.03 mg / d, respectively. 1.80 卤0.84mg / L, 1.44 卤0.86mg / L, 0.71 卤0.39mg / L, the difference was statistically significant (P 0.05). The correlation coefficient between urinary fluorine concentration and daily fluoride intake was 0.441g / d (P0.05). In the study of dose-effect relationship between cumulative fluoride intake and prevalence of dental fluorosis in children, The calculated baseline dose and 95% confidence interval (BMDL) were 1 371.11 mg and 572.98 mg respectively. [conclusion] the urinary fluorine concentration and the incidence of dental fluorosis in children were increased in the vicinity of the electrolytic aluminum factory. It may be related to the discharge of pollutants from the plant.
【作者单位】：百色市疾病预防控制中心环境职业与放射卫生科;广西医科大学公共卫生学院职业卫生和环境卫生教研室;
【分类号】：R788

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