腮腺黏膜相关淋巴组织淋巴瘤的临床特点分析

发布时间：2018-03-30 17:53

本文选题：腮腺肿瘤　切入点：黏膜相关淋巴组织淋巴瘤　出处：《临床耳鼻咽喉头颈外科杂志》2017年01期

【摘要】：目的:总结腮腺黏膜相关淋巴组织(MALT)淋巴瘤的临床特点,提高其临床诊断及治疗水平。方法:回顾性分析10例腮腺MALT淋巴瘤患者的临床表现、影像学特征、病理免疫组织化学检查结果、手术治疗及预后资料。结果:10例患者临床表现为耳垂下无痛性渐大肿块,其中累及腮腺浅叶8例,深叶2例。CT扫描为等、高软组织密度影,偶见钙化及坏死,增强扫描时肿块轻中度强化,周围增强或延迟增强。病理检查表现为弥漫性淋巴细胞浸润,并形成上皮-肌上皮岛样病灶,免疫组织化学证实其来源为B细胞淋巴瘤。10例患者均接受手术治疗,按肿瘤部位不同,分为腮腺浅叶切除术或腮腺全切除术。术后随访1~7年,均未见肿瘤复发。结论:腮腺MALT淋巴瘤诊断需结合临床、影像学及病理免疫组织学,治疗以手术切除为主,术后结合放化疗,预后良好,长期疗效还需进一步观察。
[Abstract]:Objective: to summarize the clinical features of parotid mucosa-associated lymphoid tissue malt lymphoma and to improve its clinical diagnosis and treatment. Methods: the clinical and imaging features of 10 patients with parotid gland MALT lymphoma were retrospectively analyzed. Results the clinical manifestations of 10 cases were painless and progressive masses under ear lobe, including 8 cases involving the superficial lobe of parotid gland, 2 cases of deep lobe and 2 cases of CT scanning, with high soft tissue density. Calcification and necrosis were occasionally seen, and the mass was slightly or moderately enhanced in contrast enhancement, and enhanced or delayed in surrounding areas. Pathological findings showed diffuse lymphocytic infiltration and epithelial-myoepithelial insular lesions. All the 10 patients with B-cell lymphoma were treated by operation according to the tumor location, which were divided into superficial parotid lobectomy and total parotidectomy. All patients were followed up for 1 ~ 7 years. Conclusion: the diagnosis of parotid MALT lymphoma should be combined with clinical imaging and histopathology. Surgical resection is the main treatment combined with radiotherapy and chemotherapy. The prognosis is good and the long-term curative effect needs to be further observed.
【作者单位】：江南大学附属医院(无锡市第四人民医院)耳鼻咽喉头颈外科;江南大学附属医院(无锡市第四人民医院)病理科;江南大学附属医院(无锡市第四人民医院)口腔科;
【分类号】：R739.8

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