钛表面碱酸热处理的体外实验研究
发布时间:2018-04-02 07:38
本文选题:二氧化钛 切入点:纳米网状结构 出处:《安徽医科大学学报》2017年09期
【摘要】:通过碱、稀酸、热处理在纯钛表面构建纳米级网状生物活性层,采用场发射电镜和X射线能量色散谱仪观察三组试件表面微观形貌和元素组成。小鼠骨髓间充质干细胞与三组试件共培养,体外评价试件表面的生物活性。结果表明碱酸热处理组试件表面仍呈现精细的网状结构,碱酸热处理可以脱除试件表面钠元素。体外细胞培养结果表明,碱酸热处理表面具有良好的生物活性。
[Abstract]:Nanoscale bioactive layer was constructed on the surface of pure titanium by alkali, dilute acid and heat treatment. The surface morphology and elemental composition of the three groups of specimens were observed by field emission electron microscopy and X-ray energy dispersive spectrometer. The bone marrow mesenchymal stem cells of mice were co-cultured with the three groups of specimens. The results of in vitro evaluation of the surface biological activity of the samples showed that the surface of the samples treated with alkali acid still showed fine reticular structure, and the sodium element on the surface of the samples could be removed by alkali acid heat treatment. The results of cell culture in vitro showed that the surface of the samples was treated with alkali-acid heat treatment. The surface of alkali-acid heat treatment has good biological activity.
【作者单位】: 安徽医科大学第二附属医院口腔科;安徽医学高等专科学校口腔系;
【基金】:安徽省自然科学基金(编号:1508085MH156) 安徽省学术和技术带头人科研活动经费资助项目(编号:2014H030)
【分类号】:R783.1
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本文编号:1699428
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