低能量激光照射对牙周炎的治疗效应研究

发布时间：2018-04-05 02:40

本文选题：低能量激光照射　切入点：牙周炎　出处：《科学中国人》2016年24期

【摘要】：牙周病是牙齿支持组织因炎症所致的一种最常见的口腔疾病,属于多发病,与全身健康有着密切的联系。目前,牙周病在临床的治疗上还无彻底的措施。牙周病两大主要症状是牙周袋形成与牙槽骨缺失。由于牙齿周围的细菌极不易清除,在临床上只能采取生态调整疗法,即除菌、抑菌,或者减弱细菌侵袭力的方式来防治牙周病。另外,在病患反应过程中,此疗法能抑制细胞因子、金属蛋白酶及前列腺素等活性物质的产生,降低其破坏牙周组织的能力,还能增强病患的体质,提高机体抵抗力,有利于重建牙周健康的生态系统。目前,临床上大多用传统的基本疗法来清除大部分菌斑及病原刺激物。但相关研究表明,传统治疗中手工清洁、手工刮治的方法,会对沟内上皮、结合上皮产短时的机械性损伤,从而降低牙周膜细胞的增殖力。而动物实验表明,低能量激光作用于糖尿病小鼠,能加快伤口的愈合,提示低能量激光对生物调节有一定的作用。目前,关于低能量激光生物刺激效应的研究在国内外医学领域为数不多,且主要集中在体外培养细胞实验的水平上。
[Abstract]:Periodontal disease is one of the most common oral diseases caused by inflammation in dental supporting tissue.At present, periodontal disease in clinical treatment has no thorough measures.The two main symptoms of periodontal disease are periodontal pocket formation and alveolar bone loss.Because the bacteria around the teeth are very difficult to remove, we can only take ecological adjustment therapy in clinic, that is, sterilizing, inhibiting bacteria, or weakening the invasiveness of bacteria to prevent and cure periodontitis.In addition, this therapy can inhibit the production of cytokines, metalloproteinases and prostaglandins, reduce their ability to destroy periodontal tissue, and enhance the patient's physique and body resistance.It is beneficial to rebuild the periodontal healthy ecosystem.At present, most clinical use of traditional basic therapy to remove most of the plaque and pathogenic irritants.But related studies have shown that the traditional methods of manual cleaning and manual curettage can reduce the proliferation of periodontal ligament cells by causing short-term mechanical damage to the epithelium in the sulcus and combined with the epithelium.Animal experiments showed that low energy laser could accelerate wound healing in diabetic mice, suggesting that low energy laser could play a certain role in biological regulation.At present, there are few researches on the effect of low energy laser biological stimulation in the field of medicine at home and abroad, and it is mainly focused on the level of cell culture in vitro.
【作者单位】：重庆医药高等专科学校;
【分类号】：R781.42

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