利用潮汕人群第一前磨牙牙本质天冬氨酸消旋化比率推断生物学年龄的研究

发布时间：2018-04-05 13:06

  本文选题：第一前磨牙　切入点：天冬氨酸消旋化比率　出处：《口腔医学研究》2017年05期

【摘要】：目的:探讨潮汕人群第一前磨牙牙本质天冬氨酸消旋化比率推断年龄的准确性。方法:收集潮汕人群第一前磨牙标本60例,利用高效液相色谱法检测其牙本质内天冬氨酸消旋化(D/L)比率,并与实际年龄建立回归方程;再用3例另外收集的牙本质标本检验方程的准确性。结果:潮汕人群第一前磨牙牙本质天冬氨酸消旋化(D/L)比率与年龄高度正相关(P0.001),相关系数r=0.967,消旋化速率k=6.0×10~(-4)/年,推断年龄误差SE=2.60岁。3例验证标本的误差分别是-0.3岁,+1.6岁,-2.2岁。结论:潮汕人群第一前磨牙牙本质天冬氨酸消旋化(D/L)比率可以准确推断年龄。
[Abstract]:Objective: To study the accuracy of Chaoshan population first molar dentin aspartic acid racemization ratio to estimate age. Methods: collected Chaoshan population of first premolar specimens in 60 cases, the detection of dentin in aspartic acid racemization by high performance liquid chromatography (D/L) ratio, and the regression equation is established with the actual age; and 3 cases were also collected dentin specimens test the accuracy of the equation. Results: Chaoshan population first premolar dentin aspartic acid racemization (D/L) ratio and the age of highly positive correlation (P0.001), correlation coefficient r=0.967, racemization rate k= 6 * 10~ (-4) / year, age SE=2.60 years old.3 error inference error Verify samples are -0.3 years, +1.6 years, -2.2 years old. Conclusion: Chaoshan population first molar dentin aspartic acid racemization (D/L) ratio can accurately estimate the age.

【作者单位】： 汕头大学医学院第二附属医院口腔颌面外科;汕头大学医学院法医学教研室;
【基金】：广东省医学科研基金(编号:A2016565)
【分类号】：R78
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本文编号：1714873