大鼠腮腺主导管结扎及再通后的组织学观察

发布时间：2018-04-14 15:06

本文选题：腮腺 + 再生　；参考：《实用口腔医学杂志》2014年04期

【摘要】：目的:观察腮腺主导管结扎及再通后腺体的组织学变化。方法:结扎大鼠右侧腮腺主导管,于结扎后第14天使其再通,分别于再通后第0、1、3、5、7、10、14、21天获取腮腺标本(n=5),应用HE染色和形态计量方法,观察主导管再通后腺泡、导管及间质的形态及体积分数变化。结果:腮腺组织于主导管结扎后第14天显著萎缩;再通后第3天开始,腺泡体积分数逐渐增多,导管及间质体积分数逐渐减少(P0.05);再通14 d后,腺泡、导管及间质所占体积分数均与正常对照组无显著差异(P0.05)。结论:腮腺主导管结扎14 d再通后萎缩的腺体能够再生、恢复正常。
[Abstract]:Objective: to observe the histological changes of glands after ligation and recanalization of parotid main duct.Methods: the parotid gland was ligated on the right side of the parotid gland of rats, and recanalized by the 14th angel after ligation. The parotid gland specimens were obtained from the parotid gland on the 01th day after the recanalization of the parotid gland. The specimens of the parotid gland were obtained by HE staining and morphological metrology, and the acinus after the recanalization of the dominant duct were observed.Changes in the morphology and volume fraction of ducts and stroma.Results: the parotid gland shrank significantly on the 14th day after ligation of the main duct, and the volume fraction of the acinar increased gradually and the volume fraction of the ducts and the interstitial decreased gradually on the third day after the recanalization, and the volume fraction of the ducts and the interstitial decreased gradually after 14 days of recanalization, and the acinar after 14 days of recanalization.There was no significant difference in volume fraction of catheters and stroma between the two groups (P 0.05).Conclusion: the atrophy gland of parotid gland after 14 days of ligation can regenerate and return to normal.
【作者单位】：滨州医学院附属医院口腔颌面外科;滨州医学院附属医院口腔正畸科;
【基金】：山东省医药卫生科技发展计划基金(编号:2011HW004)
【分类号】：R782.7

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