两种局麻药物在下牙槽神经阻滞麻醉中效果的比较

发布时间：2018-04-23 00:38

本文选题：阿替卡因 + 利多卡因　；参考：《中国新药与临床杂志》2017年01期

【摘要】：目的比较4%阿替卡因和2%利多卡因下牙槽神经阻滞麻醉的效果。方法对98例需拔除双侧下颌阻生第三磨牙的患者行下牙槽神经阻滞麻醉,在同一位患者两侧分别注射4%阿替卡因(试验组)和2%利多卡因(对照组)100 mg,并行高速涡轮机微创拔牙。比较两组麻醉显效时间、患者术中疼痛程度及患者血压和心率变化。结果试验组麻醉显效时间为(102.8±19.4)s,显著低于对照组[(229.0±58.7)s,P0.05]。试验组疼痛视觉模拟量表评分虽低于对照组,但组间无显著差异(P0.05)。两组麻醉时、翻瓣时、去骨时、缝合时患者的收缩压、舒张压和心率组间均无显著差异(P0.05)。结论 4%阿替卡因可代替2%利多卡因行下牙槽神经阻滞麻醉。
[Abstract]:Objective to compare the effect of 4% atracaine and 2% lidocaine on inferior alveolar nerve block. Methods Ninety-eight patients with bilateral mandibular impacted third molars were anesthetized by inferior alveolar nerve block. In the same patient, 4% Atevacaine (trial group) and 2% lidocaine (control group, 100 mg) were injected on both sides of the same patient, respectively, with a high speed turbine for minimally invasive tooth extraction. The duration of anesthesia, the degree of intraoperative pain and the changes of blood pressure and heart rate were compared between the two groups. Results the effective time of anesthesia in the experimental group was 102.8 卤19.4s, which was significantly lower than that in the control group (P 0.05). Although the scores of visual analogue scale of pain in the trial group were lower than those in the control group, there was no significant difference between the two groups (P 0.05). There was no significant difference in systolic blood pressure, diastolic blood pressure and heart rate between the two groups during anesthesia, valvuloplasty, bone removal and suture. Conclusion 4% Atevacaine can replace 2% lidocaine in inferior alveolar nerve block anesthesia.
【作者单位】：白求恩国际和平医院口腔科;通州干休所;
【分类号】：R782.054

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