西帕依固龈液治疗口臭随机对照试验的Meta分析

发布时间：2018-04-23 22:19

  本文选题：西帕依固龈液 + 口臭　； 参考：《实用口腔医学杂志》2017年01期

【摘要】：目的:系统评价西帕依固龈液治疗口臭的临床疗效。方法:计算机检索美国图书馆PubMed/MEDLINE、CNKI中国知网(总库)、维普期刊资源整合服务平台相关文献。根据Jadad量表对纳入文献进行质量评价。采用(Cochrane协作网提供的RevMan 5.3分析软件进行Meta分析。结果:共纳入8项临床随机对照研究(RCT)、608例有口臭症状患者。依据Meta分析结果,西帕依固龈液与安慰剂比较治疗口臭的评分(organoleptic score,OS)[WMD=-0.43,95%CI(-0.57,-0.29)]、菌斑指数(plaque index,PLI)[WMD=-1.59,95%CI(-1.67,-1.51)]均显示有显著差异;西帕依固龈液与两药比较治疗口臭OS[WMD=0.16,95%Cl(0.05,0.28)]效果略差且降低PLI[WMD=0.10,95%CI(0.03,0.18)]的抑菌效果也略差。西帕依固龈液与生理盐水治疗口臭临床总有效率差异有统计学意义[RR:1.64,95%CI(1.11,2.42)]。结论:西帕依固龈液治疗口臭疗效优于安慰剂,可有效降低口臭值和菌斑指数,与西药相比降低口臭值、抑菌方面稍显欠缺。
[Abstract]:Objective: to evaluate the clinical effect of cipail gingival fluid in the treatment of halitosis. Methods: the relevant documents of PubMed/ MEDLINEN CNKI CNKI (General Library, Web-based periodical Resource Integration Service platform) were searched by computer. The quality of the literature was evaluated according to the Jadad scale. Meta analysis was carried out with RevMan 5.3 software provided by Cochrane Cooperative Network. Results: a total of 608 patients with halitosis were enrolled in 8 randomized controlled trials. 渚濇嵁Meta鍒嗘瀽缁撴灉,瑗垮笗渚濆浐榫堟恫涓庡畨鎱板墏姣旇緝娌荤枟鍙ｈ嚟鐨勮瘎鍒，

本文编号：1793889