3.5代聚酰胺-胺作用时间与牙本质小管封闭效果的相关性研究

发布时间：2018-04-24 11:13

本文选题：聚酰胺-胺树枝状分子(PAMAM) + 牙本质敏感症　；参考：《牙体牙髓牙周病学杂志》2014年12期

【摘要】：目的:评估3.5代聚酰胺-胺树枝状分子(PAMAM)对牙本质小管的阻塞能力。方法:收集32个完整离体第三磨牙制备32个脱矿牙本质模型,并将其随机分为A、B、C、D 4组(n=8),分别置于3.5代PAMAM溶液中处理0、1、30、60 min后,再同时浸泡于人工唾液中再矿化2周,然后分别用傅里叶变换红外分光镜(FT-IR)、场发射扫描电镜(FE-SEM)、能谱仪(EDS)观察检测。结果:A组牙本质小管完全开放;B、C、D各组经PAMMA处理相应时间后,其大部分牙本质小管口均被矿化物封闭,B、C、D组牙本质小管封闭深度分别为(26.31±2.45)、(25.34±2.57)、(30.36±2.15)μm,3组间差异无统计学意义(P0.05);A、B、C、D 4组钙磷比值两两间差异亦均无统计学意义(P0.05)。结论:3.5代聚酰胺-胺对脱矿牙本质小管有一定的封闭作用,但其作用时间与牙本质小管的封闭效果无明显相关性。
[Abstract]:Aim: to evaluate the ability of 3.5 generation polyamide-amine dendrimer to block dentin tubules. Methods: 32 demineralized dentin models were made from 32 intact third molars in vitro, and were randomly divided into two groups: group D: Acarinine group, treated with PAMAM solution of 3. 5 generations for 30 ~ 60 min, then immersed in artificial saliva for 2 weeks. Then FT-IRT, FE-SEM and EDS were observed and detected by Fourier transform infrared spectroscope (FTIR), field emission scanning electron microscope (SEM) and energy dispersive spectrometer (EDS), respectively. Results the dentinal tubules of group A were completely open and treated with PAMMA for some time. There was no significant difference in calcium and phosphorus ratio between the three groups (26.31 卤2.45) and 25.34 卤2.57 (30.36 卤2.15) 渭 m respectively. There was no significant difference in calcium and phosphorus ratio between the three groups. Conclusion the wet-3.5 generation polyamide-amine has a certain blocking effect on demineralized dentin tubules, but there is no significant correlation between the time of action and the sealing effect of dentin tubules.
【作者单位】：广西医科大学附属口腔医院;
【基金】：广西自然科学基金项目(2011GXNSFA01829) 广西高校科学技术研究一般项目(2013YB056) 广西医疗卫生适宜技术研究开发项目(S201305-01)
【分类号】：R781.2

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