下颌骨骨折术后感染因素的回顾性研究

发布时间：2018-04-29 01:02

本文选题：下颌骨 + 骨折　；参考：《重庆医科大学》2017年硕士论文

【摘要】：目的探讨下颌骨骨折行坚固内固定术后感染相关的风险因素,为进一步完善下颌骨骨折患者围手术期的治疗管理提供依据,降低下颌骨骨折行坚固内固定术后感染发生率。方法设计病例对照研究并收集我院2006年1月-2012年12月期间下颌骨骨折坚固内固定手术患者447例,其中出现术后感染的病例为26例(实验组)。从每例发生术后感染的患者入院前2周内,随机选取1例下颌骨骨折坚强内固定术后无任何并发症的患者纳入对照组,共26例。收集整理相关的变量数据,采用SAS9.2软件包在2组间行二变量和多因素Logistic回归分析,确定与术后感染相关的因素。结果回归分析结果显示,增长的下颌骨骨折严重程度评分(OR=2.509,95%CI为1.083-5.814)以及患者欠佳的全身健康状态(OR=5.019,95%CI为1.294-19.472)是导致术后感染的相关风险因素。在二变量检验中抗生素使用天数与术后感染具有相关性(P0.05)。结论骨折的严重程度和患者欠佳的身体健康状态是下颌骨骨折术后感染的风险因素。
[Abstract]:Objective to explore the risk factors related to infection after rigid internal fixation of mandibular fracture, to provide basis for further improvement of perioperative management of mandibular fracture and to reduce the incidence of infection after rigid internal fixation of mandibular fracture. Methods A case-control study was conducted in 447 patients with rigid internal fixation of mandibular fractures from January 2006 to December 2012 in our hospital. Among them 26 cases were infected after operation (experimental group). Within 2 weeks before admission, one patient with no complications after rigid internal fixation of mandibular fracture was randomly selected as control group (n = 26). The data of related variables were collected and analyzed. The two variables and multivariate Logistic regression analysis were carried out between the two groups by SAS9.2 software package to determine the factors related to postoperative infection. Results the regression analysis showed that the increased mandibular fracture severity score (OR 2.509 95 CI = 1.083-5.814) and the patients' poor general health state (CI = 1.294-19.472) were the risk factors associated with postoperative infection. There was a correlation between the days of antibiotic use and postoperative infection in two-variable test (P 0. 05). Conclusion the severity of fracture and poor health of patients are risk factors for postoperative infection of mandibular fracture.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R782.4

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