不同正畸力作用下大鼠疼痛行为反应变化

发布时间：2018-04-30 12:40

本文选题：正畸力 + 大鼠　；参考：《郑州大学学报(医学版)》2014年03期

【摘要】：目的:观察不同正畸力作用下疼痛行为反应的变化。方法:选取78只8周龄、体重为(266.67±20.46)g的SD雄性大鼠,随机分为空白组6只和实验组(包括50 g力值组和100 g力值组)72只,空白组不做任何处理,实验组分别施加50和100 g力近中移动左侧上颌第一磨牙建立大鼠实验性牙齿移动模型,观察加力后1、2、3、5、7、14 d时的疼痛行为反应。结果:各组大鼠前30 s通过的总线数、5 min内通过的总线数、5 min内通过旷野中心的总线数、5 min内抬起行为的总时间、5 min内拭嘴行为的总时间及抗捕获行为评分比较,差异均有统计学意义(H=12.019、25.166、10.095、2.224、9.456、23.960,P均0.05);且100 g力值组疼痛反应较50 g力值组重,2 d组后5项指标比较差异均有统计学意义(P均0.05)。结论:正畸力作用下2 d时大鼠疼痛最严重,且疼痛的严重程度与所施加的正畸力值有关。
[Abstract]:Objective: to observe the changes of pain behavior under different orthodontic forces. Methods: Seventy-eight 8-week-old SD male rats weighing 266.67 卤20.46 g were randomly divided into blank group (n = 6) and experimental group (n = 72) (including 50 g force group and 100 g force group). The experimental model of tooth movement was established by applying 50 and 100 g force to the left maxillary first molar in the experimental group, and the pain behavior was observed on the 14th day after the treatment. Results: the number of buses passed within 5 min in the first 30 s of rats in each group and the total time of lifting behavior in 5 min within 5 min and the total time of swabbing in 5 min and the score of anti-capture behavior in 5 min were compared. The differences were statistically significant (P < 0.05), and there were significant differences in the pain response between the 100 g force group and the 50 g force group on the second day after 2 days of weight, and there was significant difference between the two groups (P < 0.05), and there was a significant difference between the two groups (P < 0.05) in the pain response of the 100 g force group compared with that in the 50 g force group on the second day after the pain response was significantly higher than that in the 50 g force group (P < 0.05). Conclusion: under orthodontic force for 2 days, the pain is the most serious in rats, and the severity of pain is related to the value of orthodontic force applied.
【作者单位】：郑州大学口腔医学院正畸科;郑州大学第一附属医院整形外科;
【分类号】：R783.5

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