牙周非手术治疗对慢性牙周炎患者内皮功能和动脉僵硬度的影响

发布时间：2018-05-06 11:10

本文选题：牙周炎 + 非手术治疗　；参考：《口腔医学研究》2017年12期

【摘要】：目的:探讨牙周非手术治疗对慢性牙周炎患者血管内皮功能和动脉僵硬度的影响。方法:选取于我院口腔诊疗中心就诊的慢性牙周炎患者43例(观察组)和健康者86例(健康组)作为研究对象,观察组接受牙周非手术治疗。治疗前测量两组患者的临床参数,治疗3个月后再次测量观察组的临床参数,具体包括临床牙周指数、动脉血流介导血管扩张功能(FMD,反映血管内皮功能)和肱踝脉搏波传导速度(baPWV,反映动脉僵硬度)。结果:观察组患者治疗前的FMD低于健康组[(8.02±3.13)%vs.(11.54±2.69)%],而其baPWV高于健康组[(14.48±1.97)m/s vs.(12.16±1.32)m/s],差异具有统计学意义(P0.05)。观察组治疗3个月后临床牙周指数明显改善,FMD较治疗前有所升高(9.47±3.65)%,而baPWV较治疗前有所降低(13.51±1.62)m/s,差异具有统计学意义(P0.05)。Pearson相关分析表明,观察组患者治疗前后FMD和baPWV的变化量均与其牙周探诊深度的变化量呈正相关。结论:牙周非手术治疗可明显改善慢性牙周炎患者的血管内皮功能和动脉僵硬度,可能对其心血管疾病的预防具有一定作用。
[Abstract]:Objective: to investigate the effects of periodontal non-surgical treatment on vascular endothelial function and arterial stiffness in patients with chronic periodontitis. Methods: 43 patients with chronic periodontitis (observation group) and 86 healthy subjects (healthy group) were selected as the study subjects. The observation group received periodontal non-surgical treatment. The clinical parameters of the two groups were measured before treatment, and the clinical parameters of the observation group were measured again after 3 months of treatment, including the clinical periodontal index. Arterial blood flow mediated vasodilation (FMD, reflecting vascular endothelial function) and brachial ankle pulse wave conduction velocity (BAPWV), as well as arterial stiffness. Results: before treatment, the FMD of the patients in the observation group was lower than that in the healthy group [8.02 卤3.13)%vs.(11.54 卤2.69%], but its baPWV was higher than that in the healthy group [14.48 卤1.97)m/s vs.(12.16 卤1.32)m/s]. The difference was statistically significant (P 0.05). After 3 months of treatment, the clinical periodontal index in the observation group was significantly improved by 9.47 卤3.65% and 13.51 卤1.62 m / s of baPWV, respectively. The difference was statistically significant (P 0.05). Pearson correlation analysis showed that there was no significant difference between the two groups. The changes of FMD and baPWV before and after treatment were positively correlated with the depth of periodontal probing in the observation group. Conclusion: periodontal non-surgical treatment can significantly improve vascular endothelial function and arterial stiffness in patients with chronic periodontitis and may play a role in the prevention of cardiovascular disease.
【作者单位】：恩施土家族苗族自治州中心医院口腔诊疗中心;
【分类号】：R781.42

【相似文献】