中药双黄补联合西帕依固龈液对种植体周围炎患者牙周炎症的改善作用及其临床意义

发布时间：2018-05-08 12:37

本文选题：种植体周围炎 + 双黄补　；参考：《吉林大学学报(医学版)》2017年06期

【摘要】：目的:研究中药双黄补联合西帕依固龈液对种植体周围炎患者牙周指数的影响,探讨中药双黄补联合西帕依固龈液治疗种植体周围炎的疗效。方法:将40例种植体周围炎患者随机分为对照组和中药组(n=20)。在对种植体进行龈上洁治、龈下刮治后,中药组患者采用西帕依固龈液冲洗种植周袋,同时以精细探针顺种植周袋壁缓慢插入至袋底,留置中药双黄补,缓慢后退探针使药物溢出至牙龈边缘;对照组患者采用3%双氧水、0.9%氯化钠注射液交替冲洗牙周袋,观察2组患者种植体治疗前后改良菌斑指数(mPLI)、牙周袋深度(PPD)和改良龈沟出血指数(mSBI)。采用Whatman 1号滤纸条吸取治疗前后种植体周龈沟液(PISF),检测2组患者PISF质量;采用ELISA法检测PISF中炎症因子白细胞介素1β(IL-1β)水平。结果:治疗前2组患者年龄构成、性别比例、受试牙位牙周指数、PISF质量和PISF中IL-1β水平比较差异无统计学意义(P0.05)。经不同治疗措施干预后,2组种植体周围炎患者牙周指数(PPD、mSBI和mPLI)、PISF质量以及PISF中IL-1β水平比较差异有统计学意义(P0.05)。治疗后,与对照组比较,中药组患者mSBI、mPLI、PISF质量和PISF中IL-1β水平比较差异有统计学意义(P0.05);中药组患者PPD低于对照组,但组间比较差异无统计学意义(P0.05)。结论:中药双黄补联合西帕依固龈液治疗种植体周围炎的疗效显著,可改善患者牙周指数,降低患者PISF中IL-1β水平。
[Abstract]:Objective: to study the effect of Shuanghuangbu combined with Cipayl gingival fluid on periodontal index in patients with peri-implant inflammation and to explore the curative effect of Shuanghuangbu combined with sipaie gingival fluid on periimplant periodontitis. Methods: 40 patients with periimplant inflammation were randomly divided into control group and traditional Chinese medicine group. After supragingival scaling and subgingival curettage, the patients in the traditional Chinese medicine group were treated with cippayi gingival fluid to flush the implant bags, and then inserted slowly into the bottom of the bags with fine probes, and the Chinese medicine Shuanghuang was retained. The drug overflowed to the edge of the gingival, and the patients in the control group were treated with 3% hydrogen peroxide and 0.9% sodium chloride injection alternately to flush the periodontal bag. The modified plaque index (mPLI), periodontal pocket depth (PPD) and modified gingival sulcus bleeding index (mSBII) were observed before and after implant treatment in two groups. The quality of PISF was measured by Whatman 1 filter strip before and after treatment, and the level of IL-1 尾 in PISF was detected by ELISA method. Results: before treatment, there was no significant difference in age composition, sex ratio, periodontal index (PISF) and IL-1 尾 level in PISF between the two groups. There were significant differences in periodontal index, PPD-mSBI, mPLII-PISF quality and IL-1 尾 level in PISF between the two groups after intervention with different treatment measures. After treatment, compared with the control group, there were significant differences in the quality of mSBII-mPLII-PISF and the level of IL-1 尾 in PISF between the Chinese medicine group and the control group, while the PPD in the Chinese medicine group was lower than that in the control group, but the difference between the two groups was not statistically significant (P 0.05). Conclusion: Shuanghuangbu combined with Xi Pai gingival fluid is effective in the treatment of periimplant periodontitis. It can improve periodontal index and decrease IL-1 尾 level in PISF.
【作者单位】：吉林大学口腔医院牙周病科;吉林大学口腔医院急诊科;
【基金】：吉林省中医药管理局科研项目资助课题(2016080)
【分类号】：R781.4

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