左氧氟沙星与超声引导冲洗联合治疗颌面部间隙感染效果观察

发布时间：2018-05-10 21:37

本文选题：颌面部间隙 + 感染　；参考：《中华医院感染学杂志》2014年09期

【摘要】：目的调察超声引导冲洗联合左氧氟沙星对颌面部间隙感染(MSI)的治疗效果,为MSI的临床治疗提供参考,减少耐药菌株产生。方法将82例MSI患者随机分为两组,A组40例实施脓肿切开引流术治疗,B组42例在超声引导下冲洗联合左氧氟沙星治疗,观察两组临床症状、体征缓解时间及并发症发生情况,采用SPSS17.0软件对数据进行统计分析,计量资料采用t检验;计数资料采用χ2检验。结果 B组脓腔闭合、包块消失、临床症状缓解时间为(3.1±0.4)、(5.4±1.1)、(4.2±1.3)d,均短于A组的(4.5±0.6)、(7.2±1.4)、(5.3±1.2)d,两组比较差异有统计学意义(P0.05);治疗后总有效率B组为97.62%,高于A组的80.00%(P0.05);败血症、呼吸道梗阻、纵隔感染等并发症发生率B组为11.90%、A组为30.00%,两组比较差异有统计学意义(P0.05)。结论超声引导下冲洗联合左氧氟沙星治疗MSI,可加快包块消失,促进脓腔闭合,术后不留瘢痕,对患者颌面部美观影响较小,值得临床推广应用。
[Abstract]:Objective to evaluate the efficacy of ultrasound guided irrigation combined with levofloxacin in the treatment of maxillofacial space infection and to provide reference for clinical treatment of MSI and to reduce the production of drug-resistant strains. Methods Eighty-two patients with MSI were randomly divided into two groups: group A (n = 40) treated with abscess incision and drainage, group B (n = 42) treated by ultrasound guided irrigation combined with levofloxacin, and the clinical symptoms, signs remission time and complications were observed. SPSS17.0 software was used to analyze the data, t test was used for measuring data and 蠂 2 test was used for counting data. Results in group B, the purulent cavity was closed, the mass disappeared, and the clinical symptom relief time was 3.1 卤0.4, 5.4 卤1.1, 4.2 卤1.3 days, which was shorter than that in group A (4.5 卤0.6, 7.2 卤1.4, 5.3 卤1.2), the difference was statistically significant (P0.05), the total effective rate of group B was 97.622.It was higher than that of group A (80.005), septicemia, obstruction of respiratory tract, respiratory tract obstruction, The incidence of complications such as mediastinal infection in group B was 11.90% and 30.005 in group A, with a significant difference between the two groups (P 0.05). Conclusion Ultrasound-guided irrigation combined with levofloxacin in the treatment of MSI can accelerate the disappearance of mass, promote the closure of pus cavity and leave no scar after operation, and has little effect on the aesthetic appearance of the maxillofacial region of the patients. It is worthy of clinical application.
【作者单位】：杭州师范大学附属医院口腔科;杭州口腔医院口腔科;
【基金】：浙江省自然科学基金资助项目(Y206192)
【分类号】：R782

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