PRF复合GBR技术在牙槽嵴位点保存中的应用研究

发布时间：2018-06-02 03:43

本文选题：位点保存 + 富血小板纤维蛋白　；参考：《中国口腔种植学杂志》2017年03期

【摘要】：目的:观察富血小板血纤维蛋白(PRF)复合引导骨再生(GBR)技术在牙槽嵴位点保存中的应用效果及骨再生情况。方法:选取本院口腔科就诊上前牙外伤患者5例,分为对照组和实验组,二组分别为同一患者双侧对称同名牙,实验组行PRF膜+Bio-Oss骨粉+海奥生物膜位点保存术,对照组行Bio-Oss骨粉+海奥生物膜位点保存术。术后2周、4周、6周、8周、12周X线片应用MATLAB软件进行术区灰度值测量,术后半小时、6周及12周锥形束CT(CBCT)应用simplant软件行牙槽嵴顶下2mm、4mm、6mm三个位点牙槽骨宽度、高度及术区骨质密度测量。结果:二组X线片灰度值差异有统计学意义(P0.01),二组各时期X线片灰度值的差值差异均有统计学意义(P0.01),相关性检验示与时间有相关性(P0.01),二组术后即刻及术后12周牙槽嵴顶下2mm、4mm、6mm宽度、牙槽嵴顶到对颌牙切端平面高度差异无统计学意义(P0.05),CBCT术区骨密度值差异有统计学意义(P0.05),相关性检验示与时间有相关性(P0.01)。结论:PRF配合GBR技术与单纯使用GBR技术进行位点保存术均能有效减少牙拔除术后牙槽骨宽度及高度的吸收,并且PRF可以促进新骨生成以及人工骨粉向新骨转化,同时期较单纯GBR技术成骨速度快。
[Abstract]:Objective: to observe the effect of platelet rich blood fibrin (PRF) combined with guided bone regeneration (GBR) technique in alveolar ridge preservation and bone regeneration. Methods: five patients with anterior teeth trauma were divided into two groups: control group and experimental group. The two groups were bilateral symmetric teeth of the same patient. The experimental group was treated with PRF membrane Bio-Oss bone powder sea auricle biofilm site preservation. The control group was treated with Bio-Oss bone powder, sea auricle biofilm site preservation. The gray value of the operation area was measured by MATLAB software. The width of alveolar bone was measured by simplant software at 2 mm, 4 mm and 6 mm below the top of alveolar crest with simplant software at 6 weeks and 12 weeks after operation, and the width of alveolar bone at 3 sites was measured by MATLAB software in the second week, 4 weeks, 8 weeks, and 12 weeks after operation, and the width of alveolar bone was measured by simplant software. Height and bone density were measured. Results: there was significant difference in gray value of X-ray film between the two groups (P 0.01). The difference of gray value of X ray film in two groups was statistically significant (P 0.01). The correlation test showed that there was a correlation with time (P 0.01). The teeth of both groups were immediately after operation and 12 weeks after operation. The width of the alveolar ridge was 4 mm and 6 mm below the top of the alveolar ridge. There was no significant difference between the top of alveolar ridge and the height of the incisal end of maxillary teeth. There was significant difference in bone mineral density (BMD) between CBCT and P0.05. The correlation test showed that there was a correlation between BMD and time. Conclusion GBR combined with GBR and GBR can effectively reduce the width and height of alveolar bone resorption, and PRF can promote the formation of new bone and the transformation of artificial bone powder to new bone. At the same time, the rate of osteogenesis was faster than that of GBR alone.
【作者单位】：山西医科大学口腔医学系;山西医科大学第一医院口腔科;
【分类号】：R783.6

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