颌骨放射性骨坏死的影像学特点

发布时间：2018-06-02 13:46

本文选题：放射性骨坏死 + 头颈部　；参考：《口腔医学研究》2017年10期

【摘要】：目的:评价头颈部恶性肿瘤治疗后颌骨放射性骨坏死的影像学特点。方法:对68例颌骨放射性骨坏死的临床、影像资料进行回顾性研究,包括原发瘤类型与部位、放疗结束至出现放射性骨坏死的时间、受累颌骨的影像学特点以及术后病理诊断等。结果:原发瘤主要是鼻咽癌和口腔癌。颌骨放射性骨死部位绝大多数(63例,91.18%)是下颌骨体或下颌体-升支区,较多(49例,72.06%)发生在放疗后5年内。骨小梁消失或结构紊乱、皮质中断是常见影像学表现,其次是死骨片与骨硬化,少数病例中可观察到病变骨邻近的软组织或肌肉增厚与强化。结论:CT是评价颌骨放射性骨坏死的较可靠方法,可明确病变范围并有利于鉴别肿瘤复发。
[Abstract]:Objective: to evaluate the imaging features of radiation-induced osteonecrosis of jaws after treatment of malignant tumors of head and neck. Methods: the clinical and imaging data of 68 patients with osteonecrosis of jaws were retrospectively studied, including the type and location of primary tumor, the time from the end of radiotherapy to the occurrence of radiation osteonecrosis. Imaging features and postoperative pathological diagnosis of the involved jaw. Results: primary tumors were mainly nasopharyngeal carcinoma and oral carcinoma. The vast majority of the dead sites of the radioactive bone in the jaws (63 cases, 91.18) were the mandibular body or the mandibular body-ascending branch area, and more 49 cases (72.06) occurred within 5 years after radiotherapy. The bone trabeculae disappeared or the structure was disordered, cortical disruption was the most common imaging manifestation, followed by the dead bone slice and bone sclerosis. In a few cases, the soft tissue or muscle adjacent to the lesion bone was thickened and strengthened. ConclusionCT scan is a reliable method for evaluating osteonecrosis of jaws, which can identify the extent of lesion and help to differentiate the recurrence of the tumor.
【作者单位】：武汉大学口腔医院修复科;武汉大学口腔医院口腔颌面外科;武汉大学口腔医院放射科;
【基金】：第三批武汉中青年医学骨干人才培养工程
【分类号】：R739.91;R782

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