兔下颌牙移动模型的建立

发布时间：2018-06-07 06:53

本文选题：下颌 + 牙移动　；参考：《激光杂志》2014年03期

【摘要】：目的:建立兔下颌牙齿移动的动物模型,为研究下颌牙移动提供实验基础。方法:新西兰大白兔12只,分为4组(A、B、C、D),以75gf为初始力使左下颌第一前臼齿向近中移动,分别以A组5日、B组10日、C组15日、D组20日后测量左下颌第一前臼齿移动距离,取左下颌第一前臼齿及其牙周膜牙槽骨标本,脱钙制作切片,苏木精—伊红(Hematoxylin-eosin,HE)染色。结果:12只新西兰大白兔术后与术前相比精神食欲均无明显改变,左下颌第一前臼齿向近中移动,移动速度随时间延长逐渐变缓。切片见压力侧牙周膜明显变窄,多核巨细胞位于牙槽骨表面,未见玻璃样变区;张力侧牙周膜变宽,牙周膜内血管充血扩张。结论:在75gf初始力作用下,10日内牙齿移动快速、稳定,牙齿移动约10日-15日牙周改建活跃。利用新西兰大白兔为实验动物,建立下颌牙移动的模型,用75 gf为初始力能够达到较好移动下颌第一前臼齿的目的,可以应用于研究下颌牙移动的研究中。
[Abstract]:Objective: to establish an animal model of mandibular tooth movement in rabbits and provide experimental basis for the study of mandibular tooth movement. Methods: twelve New Zealand white rabbits were divided into 4 groups. The first premolar tooth of left mandible was moved to the proximal center with 75gf as the initial force. The first premolar movement distance of left mandible was measured after 20 days after 15 days in group B and 10 days in group B and C respectively. The first premolar of left mandible and the alveolar bone of periodontal ligament were taken and decalcified to make sections. Hematoxylin-eosin HEhe was stained with Hematoxylin-eosin (Hematoxylin-eosin). Results there was no significant change in mental appetite in 12 New Zealand rabbits after operation, and the first premolar of the left mandible moved to the proximal center, and the moving speed gradually slowed down with the prolongation of time. It was found that the pressure side periodontal membrane became narrower, the multinucleated giant cells were located on the surface of alveolar bone, and the tension side of the periodontal membrane became wider, and the blood vessels in the periodontal ligament became congested and dilated. Conclusion: under the action of 75gf initial force, tooth movement is fast and stable within 10 days, and tooth movement is active in 10-15 days. The model of mandibular tooth movement was established by using New Zealand white rabbit as experimental animal. Using 75gf as the initial force, the first premolar could be better moved. It can be used in the study of mandibular tooth movement.
【作者单位】：重庆市合川区人民医院;重庆医科大学附属口腔医院;
【分类号】：R783.5

【共引文献】