碳酸氢钠含漱液预防唇裂术后切口感染的临床研究

发布时间：2018-06-07 22:07

本文选题：碳酸氢钠含漱液 + 唇腭裂　；参考：《中华医院感染学杂志》2014年04期

【摘要】：目的观察碳酸氢钠含漱液预防唇腭裂患儿术后切口感染的作用,以寻找降低唇裂术后切口感染的方法,提高唇裂手术成功率。方法选取2010年4月-2013年3月的67例唇腭裂手术患儿为研究对象,随机分为对照组32例、观察组35例,对照组和观察组术后含漱液分别使用生理盐水和碳酸氢钠进行预防切口感染,比较两组治疗后在切口感染及感染相关指标的差异性,采用SPSS13.0软件进行数据分析。结果对照组32例患儿中术后发生切口感染10例,感染率为31.25%,观察组35例患儿中发生切口感染5例,感染率为14.28%,两组比较差异有统计学意义(P0.05);Ⅰ、Ⅲ级切口清洁度对照组患儿分别占31.25%、40.63%;观察组分别占54.29%、14.28%,两组比较差异有统计学意义(P0.05);两组患儿感染相关性指标白细胞计数、超敏蛋白、白介素-6、肿瘤坏死因子-α含量在入院时比较,差异均无统计学意义,治疗1周后均有所改善,观察组较对照组改善更加显著,差异有统计学意义(P0.05);创面愈合不良率观察组为2.86%、对照组为18.75%,两组比较差异有统计学意义(P0.05)。结论碳酸氢钠含漱液可降低唇腭裂患儿术后切口感染发生率,且安全性好。
[Abstract]:Objective to observe the effect of sodium bicarbonate gargle on the prevention of postoperative incision infection in children with cleft lip and palate. Methods from April 2010 to March 2013, 67 children with cleft lip and palate were randomly divided into control group (n = 32) and observation group (n = 35). Saline and sodium bicarbonate were used to prevent incision infection in control group and observation group respectively. The difference of wound infection and infection related indexes after treatment was compared. SPSS 13.0 software was used to analyze the data. Results among 32 children in the control group, 10 cases had incision infection and the infection rate was 31.25%. In the observation group, 5 cases had incision infection and the infection rate was 14.28%. The difference between the two groups was statistically significant (P 0.05). The third grade incision cleanliness degree control group accounted for 31.25% 40.63, the observation group accounted for 54.29% and 14.285.The difference between the two groups was statistically significant (P 0.05); the infection related index WBC count, hypersensitivity protein, hypersensitivity protein in the two groups were significantly higher than those in the control group. The levels of interleukin-6 and tumor necrosis factor-伪 were not significantly different at admission, but were improved after one week of treatment, and the improvement in the observation group was more significant than that in the control group. The difference was statistically significant (P 0.05), the rate of wound healing failure was 2.86 in the observation group and 18.75 in the control group. The difference between the two groups was statistically significant (P 0.05). Conclusion Sodium bicarbonate gargle can reduce the incidence of incision infection in children with cleft lip and palate.
【作者单位】：沈阳医学院附属中心医院口腔科;
【基金】：辽宁省卫生厅规划基金项目(LW-2010B-029) 辽宁省自然科学基金资助项目(20102220)
【分类号】：R782.2

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