口腔鳞状细胞癌在颈部淋巴结包膜外侵犯方向的初步探讨

发布时间：2018-06-13 11:01

本文选题：口腔癌 + 淋巴结转移　；参考：《实用口腔医学杂志》2014年05期

【摘要】：目的:探讨口腔鳞状细胞癌在颈部淋巴结的包膜外侵犯(ECS)在各淋巴结分区的浸润方向的差异性。方法:纳入术后病理证实颈部淋巴结转移阳性患者57例。对淋巴结ECS方向的差异性及ECS与病灶T分级、浸润厚度、分化程度,淋巴结大小等之间的关系进行相关分析。结果:57例患者中,30例发生ECS,发生ECS的淋巴结共78个(转移阳性淋巴结共174个),ECS在淋巴结浅面的发生频次为66,深面为51。其中Ⅰ区发生ECS者29个淋巴结,浅面ECS频次为26,深面为13(P0.05)。其他各区ECS的浸润方向差异无显著性。ECS发生率与原发灶T分期无明显相关性(P0.05);与原发灶浸润厚度(P0.05)、肿瘤分化程度(P0.05)及淋巴结直径(P0.01)相关。结论:口腔鳞癌颈部Ⅰ区淋巴结浅面发生ECS的概率较深面大。颈淋巴结ECS的发生率与口腔癌肿瘤浸润厚度、淋巴结直径正相关,与肿瘤分化程度负相关。
[Abstract]:Objective: To investigate the difference in the infiltration of ECS in the lymph node region of the cervical lymph nodes (ECS) in the cervical lymph nodes. Methods: the difference in the ECS direction of the lymph nodes, the difference in the lymph node ECS direction, the ECS and the focus of the lymph node, the thickness of the invasion, the degree of differentiation, the size of the lymph nodes, and so on, were included. Results: among the 57 patients, 30 had ECS and 78 ECS lymph nodes (174 metastatic lymph nodes). The frequency of ECS in the superficial lymph nodes was 66, the deep surface was 51. of which 29 lymph nodes occurred in the ECS region, the superficial ECS frequency was 26 and the deep surface was 13 (P0.05). The difference of the infiltration direction of the ECS in the other areas was different. There was no significant correlation between the incidence of non significant.ECS and the T staging of primary foci (P0.05). It was related to the thickness of primary focal invasion (P0.05), the degree of differentiation of tumor (P0.05) and the diameter of lymph node (P0.01). Conclusion: the probability of ECS in the superficial lymph node of the cervical lymph node in the neck of oral squamous cell carcinoma is larger. The incidence of ECS in cervical lymph node and the thickness of the tumor infiltration of the oral cancer, and the infiltration of the tumor in the oral cavity. Positively correlated with diameter and negatively correlated with tumor differentiation.
【作者单位】：中南大学湘雅二医院口腔颌面外科;
【分类号】：R739.8

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