生物活性玻璃用于缓解活髓牙全冠预备后敏感的效果评价

发布时间：2018-06-16 05:17

本文选题：生物活性玻璃 + 牙本质过敏　；参考：《北京大学学报(医学版)》2017年04期

【摘要】：目的:评价45S5型生物活性玻璃粉末缓解活髓牙预备后敏感的临床疗效。方法:按照临床试验纳入标准和排除标准招募受试者,纳入活髓牙需行全冠修复患者18例,共31颗牙齿。采用自身前后对照、单盲的研究方法,先后涂布安慰剂(氧化锌粉末)和45S5型生物活性玻璃脱敏剂于受试牙上,并在基线时和应用安慰剂及生物活性玻璃粉末后,分别采用压力敏感探针法和冷空气喷吹法测量牙齿敏感程度,同时记录患者牙齿敏感的Tactile值、患者主观视觉模拟评分量表(visual analogue scale,VAS)数值和术者客观Schiff评分。结果:基线时和应用安慰剂及生物活性玻璃后测量到的Tactile值分别为(29.03±9.44)g、(29.68±9.48)g和(44.19±11.19)g,冷空气刺激VAS值分别为(50.79±22.92)mm、(46.63±22.06)mm和(30.90±20.30)mm,术者Schiff评分分别为2.13±0.67、1.97±0.66和1.42±0.56。统计分析结果表明,应用生物活性玻璃粉末后的Tactile值、冷空气刺激VAS值、术者Schiff评分与基线时和应用安慰剂后差异均有统计学意义(P0.05),而基线时和应用安慰剂后Tactile值、冷空气刺激VAS值、术者Schiff评分差异无统计学意义(P0.05),Schiff评分的差异与性别、牙位、是否二次备牙相关。结论:45S5型生物活性玻璃粉末对于活髓牙预备后的牙齿敏感有缓解作用。
[Abstract]:Objective: to evaluate the clinical efficacy of 45 S 5 bioactive glass powder in relieving the sensitivity of active pulp teeth. Methods: according to the criteria of clinical trial inclusion and exclusion, 18 patients (31 teeth) with total crown repair were recruited. In this study, placebo (zinc oxide powder) and 45S5 bioactive glass desensitizer were applied to the teeth before and after self-control and single-blind study, and at baseline and after the application of placebo and bioactive glass powder. The sensitivity of teeth was measured by pressure sensitive probe method and cold air injection method. The values of Tactile, subjective visual analogue scale (VAS) and objective Schiff score were recorded. Results: the values of Tactile measured at baseline, placebo and bioactive glass were 29.03 卤9.44g, 29.68 卤9.48g and 44.19 卤11.19g, respectively, while the values of cold air stimulated VAS were 50.79 卤22.92ng, 46.63 卤22.06)mm and 30.90 卤20.30mm. the Schiff scores were 2.13 卤0.671.97 卤0.66 and 1.42 卤0.56mm. The results of statistical analysis showed that there were significant differences in Tactile value, VAS value after using bioactive glass powder, Schiff score of the operator with baseline and placebo, and Tactile value with baseline and placebo, respectively. There was no significant difference in Schiff score between the two groups after cold air stimulation (VAS). The difference of Schiff score was related to sex, tooth position and secondary tooth preparation. Conclusion\%\
【作者单位】：北京大学口腔医学院·口腔医院修复科口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室;
【分类号】：R783.3

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