右美托咪定滴鼻应用于小儿唇腭裂手术的效果研究

发布时间：2018-06-29 12:18

本文选题：右美托咪定 + 滴鼻　；参考：《国际口腔医学杂志》2016年04期

【摘要】：目的观察唇腭裂患儿术前经鼻滴入右美托咪定对术前紧张情绪、父母分离焦虑、面罩接受程度和术后躁动的影响。方法选择行唇腭裂修复术患儿120例,年龄6月~3岁,随机分为2组:A组术前30 min经鼻滴入生理盐水0.02 m L·kg-1,B组滴入右美托咪定2μg·kg~(-1)。观察和记录患儿入睡时间、术前镇静评分、分离焦虑评分、面罩吸入诱导接受度评分和术后躁动评分。结果 B组患儿入睡时间为(10.52±5.34)min。在给药后30 min的镇静评分、与父母的分离焦虑评分、面罩接受程度评分、术后躁动评分中,B组明显优于A组,差异有统计学意义(P0.05)。结论唇腭裂患儿术前经鼻滴入右美托咪定,可以产生良好的术前镇静作用,改善与父母的分离焦虑,提高面罩接受度,并可显著抑制术后躁动。
[Abstract]:Objective to observe the effects of dexmetomidine on preoperative tension, parental separation anxiety, mask acceptance and postoperative restlessness in children with cleft lip and palate. Methods 120 children with cleft lip and palate, aged 6 months and 3 years old, were randomly divided into two groups: group A (n = 30) received normal saline (0.02 mL 路kg ~ (-1) 30 min before operation and group B (n = 30) with dexmetomidine (2 渭 g 路kg ~ (-1). The time of falling asleep, preoperative sedation score, separation anxiety score, face mask induction acceptance score and postoperative restlessness score were observed and recorded. Results the time of falling asleep in group B was (10.52 卤5.34) min. At 30 min after administration, sedation score, separation anxiety score from parents, face mask acceptance score and postoperative restlessness score were significantly better in group B than in group A (P0.05). Conclusion Transnasal instillation of dexmetomidine in children with cleft lip and palate before operation can produce good preoperative sedation, improve anxiety of separation from parents, increase face mask acceptance, and significantly inhibit postoperative restlessness.
【作者单位】：北京大学口腔医院麻醉科;
【分类号】：R782.054

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