374例唾液腺肿瘤临床病例分析

发布时间：2018-07-14 08:37

【摘要】：目的：了解唾液腺肿瘤的构成特点，发病情况，探讨合理治疗方法。方法：通过福建医科大学附属第一医院口腔颌面外科2009年9月-2013年12月期间收治的374例唾液腺肿瘤病例的临床资料进行回顾性分析。了解唾液腺肿瘤的构成比、发病年龄。利用卡方检验，检验肿瘤类型、肿瘤部位与发病年龄和性别的关联，检验水准P=0.05。结果：唾液腺肿瘤好于发腮腺、颌下腺、腭部小涎腺，这三个部位为涎腺肿瘤原发部位的前三位，本组病例中良性肿瘤285例，占总体76.4%，恶性肿瘤89例。多形性腺瘤、腺淋巴瘤、基底细胞腺瘤是良性肿瘤的前三位，本院收治374例病例中有11例多次复发的多形性腺瘤，复发原因可能是首次手术方式的不恰当。腺样囊性癌、腺泡细胞癌及粘液表皮样癌为恶性肿瘤好发的前三位。良性肿瘤平均发病年龄为47.3岁，恶性肿瘤的平均发病年龄为50.1岁结论：腮腺为唾液腺肿瘤的高发部位，良性肿瘤比恶性肿瘤多见，多形性是良性肿瘤中最多见的，且多形性腺瘤是良性肿瘤中最易复发的，，该组病例多形性腺瘤的复发率为5.97%。性别与唾液腺的组织病理类型有相关性。
[Abstract]:Objective: to understand the constitution and incidence of salivary gland tumor and to explore the reasonable treatment. Methods: the clinical data of 374 patients with salivary gland tumor treated in oral and maxillofacial surgery of the first affiliated Hospital of Fujian Medical University from September 2009 to December 2013 were retrospectively analyzed. To understand the constitution ratio of salivary gland tumor and the age of onset. Using chi-square test to test tumor type, tumor location and age and sex, test level P0. 05. Results: salivary gland tumors were better than parotid gland, submandibular gland and small salivary gland of palate. These three sites were the first three primary sites of salivary gland tumor. In this group, 285 cases were benign tumors, accounting for 76.4% of the total and 89 cases were malignant tumors. Pleomorphic adenomas, and basal cell adenomas are the first three benign tumors. Among 374 cases, 11 had multiple recurrent pleomorphic adenomas. The reason of recurrence may be the improper first operation. Adenoid cystic carcinoma, acinar cell carcinoma and mucoepidermoid carcinoma are the first three most common malignant tumors. The mean age of benign tumors was 47.3 years old, and the mean age of malignant tumors was 50.1 years. Conclusion: parotid gland is the most common site of salivary gland tumors, benign tumors are more common than malignant tumors, and pleomorphism is the most common among benign tumors. The recurrence rate of pleomorphic adenoma was 5.97. Sex was correlated with histopathological type of salivary gland.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R739.87

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