48例女性油漆工发生新生儿唇腭裂致病因素分析

发布时间：2018-07-17 07:53

【摘要】：目的:探讨发生新生儿唇腭裂的女性油漆工致病因素,为预防唇腭裂提供临床依据。方法:回顾性分析该院2009年3月~2012年10月收治唇腭裂患儿及产前检查过程中筛查出唇腭裂并行引产胎儿48例临床病史资料,总结并分析可能致病因素。结果:48例患儿母亲均为油漆工,且怀孕3个月前均正常工作,其中怀孕时间为工作后0.5年、工作后0.5~1.5年、工作后1.5~3年及工作后3年以上例数分别为4例、10例、11例、23例,所占百分比分别为8.4%、20.8%、22.9%、47.9%;工作后3年以上怀孕女性油漆工怀有唇腭裂胎儿所占百分比明显高于工作后3年以内怀孕者,组间比较差异有统计学意义(P0.05)。结论:唇腭裂胎儿出现与母亲接触油漆有关,且其发生与工作时间密切相关,有关部门应做好优生优育及职业病防护相关知识宣传,提醒孕妇要增强职业防护意识,积极参加孕前及孕期检查,从而有效降低唇腭裂发生风险,提高生育质量。
[Abstract]:Objective: to explore the pathogenic factors of female lacquer in neonatal cleft lip and palate and to provide clinical basis for the prevention of cleft lip and palate. Methods: from March 2009 to October 2012, 48 cases of cleft lip and palate with induced labor were screened during prenatal examination, and the possible pathogenic factors were analyzed. Results all the mothers of the 48 cases were painters, and they all worked normally before 3 months of pregnancy. The pregnancy time was 0.5 years after working, 0.5 ~ 1.5 years after work, 1.5 ~ 3 years after work and 23 cases after 3 years of work, respectively. The percentage of pregnant female painters with cleft lip and palate after 3 years of work was significantly higher than that of pregnant women within 3 years after work (P0.05). Conclusion: the occurrence of cleft lip and palate fetus is related to the mother's contact with paint, and its occurrence is closely related to working hours. The departments concerned should publicize the knowledge of eugenics and occupational disease prevention, and remind pregnant women to enhance their awareness of occupational protection. Actively participate in pre-pregnancy and pregnancy examinations to effectively reduce the risk of cleft lip and palate and improve fertility quality.
【作者单位】：河南科技大学第一附属医院口腔颌面外科;
【分类号】：R782.2

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