延期加载对微种植体稳定性和骨改建的影响

发布时间：2018-09-10 15:49

【摘要】：目的:本研究拟通过共振频率分析法结合组织学观察评价延期加载正畸牵引力对微种植体稳定性及周围骨组织改建的影响。方法:选用12只雄性新西兰兔,将48枚微种植体(AbsoAnchor,Dentos,Korea)植入于双侧兔胫骨内,每侧胫骨各植入两枚。植入后28天每侧两个微种植体间放置镍钛拉簧,右侧加载180g牵引力,左侧不加力。动物分别于植入后31天、35天、42天及56天处死(n=3)。在植入、加载及动物处死时对所有微种植体进行共振频率分析,测量种植体稳定性系数(ISQ),采用配对t检验比较加载组与非加载组的差异。对所有标本脱钙切片后进行组织学观察。结果:(1)非加载侧微种植体在植入后31天种植体-骨界面呈现为大量的编织骨,56天时新生骨改建成熟为致密的板层骨。加载侧与非加载侧相比在植入后31天、35天、42天和56天各时间点的骨组织改建未见明显差异。(2)共振频率分析显示,微种植体植入后ISQ值逐渐升高,加载侧及非加载侧在植入当天的ISQ值分别为20.40±2.87和20.98±3.17;植入后56天ISQ值升高至39.50±2.05和36.33±2.30。加载组和非加载组在各时间点ISQ值均无统计学差异(P0.05)。结论:微种植体植入28天后加载180g牵引力对微种植体稳定性和周围骨组织改建无影响。
[Abstract]:Aim: to evaluate the effects of delayed loading orthodontic traction on the stability of microimplants and the remodeling of bone tissue around microimplants by means of resonance frequency analysis (RFA) and histological observation. Methods: twelve male New Zealand rabbits were selected and 48 microimplants (AbsoAnchor,Dentos,Korea) were implanted into bilateral tibia. On the 28th day after implantation, Ni-Ti tension spring was placed between two microimplants on each side, 180 g traction was loaded on the right side and no additional force was applied on the left side. The animals were killed 31 days, 35 days, 42 days and 56 days, respectively. Resonance frequency analysis was performed on all microimplants during implantation, loading and animal execution. The stability coefficient of implants was measured by (ISQ),. The difference between the loaded group and the non-loaded group was compared by paired t test. Histological observation was performed on all specimens after decalcification. Results: (1) on the 31st day after implantation, the implant-bone interface of the unloaded microimplants presented as a large number of braided bone at 56 days after implantation, the new bone remodeled and matured into a dense lamellar bone. There was no significant difference in bone tissue remodeling between the loading side and the non-loaded side at the 31d, 35d, 42nd and 56d after implantation. (2) Resonance frequency analysis showed that the ISQ value increased gradually after microimplant implantation. The ISQ values of the loading side and the non-loading side were 20.40 卤2.87 and 20.98 卤3.17 on the day of implantation, respectively, and the ISQ values increased to 39.50 卤2.05 and 36.33 卤2.30 on the 56th day after implantation. There was no significant difference in ISQ between the loading group and the non loading group at each time point (P0.05). Conclusion: after 28 days of microimplant implantation, 180 g tractive force has no effect on the stability of microimplant and bone tissue remodeling.
【学位授予单位】：上海交通大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R783.5

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