种植体周围细菌感染患者病原菌分布及耐药性分析

发布时间：2018-09-11 21:22

【摘要】：目的研究与分析种植体周围细菌感染患者病原菌分布情况及耐药性,为种植体周围细菌感染的防控与治疗提供参考依据。方法选取医院2013年1月-2016年6月45例种植体周围细菌感染患者为研究对象,对其病原菌分布情况进行统计,并分析厌氧菌的耐药性;采用美国BD公司phoenix100全自动细菌鉴定仪进行菌株检测;采用全自动细菌鉴定仪对厌氧菌耐药性进行检测;采用SPSS16.0软件对数据进行统计分析。结果 45例种植体周围细菌感染患者共检出82株病原菌,其中厌氧菌56株占68.29%,需氧菌17株占20.73%,有益菌9株占10.98%,厌氧菌所占比例明显高于需氧菌和有益菌,菌落计数也存在明显差异,且差异均有统计学意义(P0.05),口腔链球菌、牙龈卟啉单胞菌、中间普雷沃菌等厌氧菌是常见的致病菌;厌氧菌对苯唑西林和克林霉素的耐药率相对较高,明显高于对其他药物的耐药率,差异均有统计学意义(P0.05)。结论种植体周围细菌感染患者病原菌以厌氧菌为主,且其耐药性也有自身特点,应针对其特点进行针对性防控及治疗。
[Abstract]:Objective to study and analyze the distribution and drug resistance of pathogenic bacteria in patients with bacterial infection around implants, and to provide a reference for the prevention, control and treatment of bacterial infections around implants. Methods from January 2013 to June 2016, 45 patients with bacterial infection around implants were selected as the study objects, the distribution of pathogens was analyzed, and the drug resistance of anaerobic bacteria was analyzed. The strains were detected by phoenix100 automatic bacteria identification instrument of BD company in USA, the drug resistance of anaerobic bacteria was detected by automatic bacterial identification instrument, and the data were analyzed by SPSS16.0 software. Results A total of 82 strains of pathogens were detected in 45 patients with bacterial infection around implants, of which 56 strains were anaerobic bacteria (68.29), 17 aerobic bacteria (20.73m) and 9 beneficial bacteria (10.98%). The proportion of anaerobic bacteria was significantly higher than that of aerobic bacteria and beneficial bacteria. There were also significant differences in colony counts, and the differences were statistically significant (P0.05). Oral streptococcus, porphyromonas gingivalis, Prevobacter intermedia and other anaerobic bacteria were common pathogens, and the resistance rate of anaerobes to oxacillin and clindamycin was relatively high. The rate of drug resistance was significantly higher than that of other drugs, and the difference was statistically significant (P0.05). Conclusion anaerobic bacteria are the main pathogens in patients with bacterial infection around implants, and their drug resistance also has its own characteristics.
【作者单位】：荆门市第一人民医院口腔科;
【基金】：湖北省荆门市引导性科研项目(YDKY2015004)
【分类号】：R783.6

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