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基于MRI的辽宁汉族成人颅面部三维重建及测量分析研究

发布时间:2018-10-24 19:10
【摘要】:目的 1.利用可重复测量的颅面部软组织标志点,开发一种可靠的三维软组织分析方法。 2.获得辽宁汉族地区成年人正常颅面部三维软组织形态的基本均值和各个部分的基本比例关系,为临床医学、法医人类学提供基础数据。 方法 采用GE超导1.5T MRI扫描仪对100例(女性50例,男性50例)辽宁汉族成人进行头颈联合扫描。纳入标准:身体健康,发育正常,无面部畸形和瘢痕,上下颌牙齿排列整齐,牙与牙弓形态正常,颅颌关系协调,磨牙为安氏Ⅰ类关系,,排除面部整形、正畸矫正、手术史及拍摄MRI禁忌的情况,年满18岁。利用VGStduio2.2MAX软件对扫描的DICOM格式的数据进行三维颅面重建,通过透明度及灰度值的调节以及恰当的使用过滤器和表面测定,从而得到清晰的三维重建图,配合三维的切面图从而确定颅面部软组织上53个标志点,获得决定面部形态的10个角度。再将标志点的坐标通过WinEDMA1.0.1软件获取各标志点之间的距离共31项,建立51项水平、垂直向比例指数。测量结果经SPSS17.0软件包统计分析,并进行男性、女性两组的t检验。 结果 1.通过MRI三维重建,实现颅面部软组织三维测量,包括53个标志点,92项测量项目。颅面部测量的标志点间的距离共31项,男女之间差异有统计学意义的共有21项(P<0.05);角度测量共10项,有统计学意义的有2项(P<0.05);颅面部各部分的基本比例关系共有51项,有统计学意义的有14项(P<0.05)。 2.颅面部软组织三维测量中,不够准确的点主要涉及下颌角点、颧点和耳部的几个标志点。本系统具有较高的精确度,满足人体测量要求。 结论 1.基于MRI的颅面部软组织三维测量系统可以作为一种可靠的三维软组织分析方法。 2.辽宁地区汉族成年人正常颅面部形态的三维测量显示:男、女之间的基本均值有明显的差异;而各个部分的面部比例关系和角度测量差异并不大。我们还需要在以后的研究中对颅面部软组织的三维信息做进一步的调查,以便于三维软组织诊断与未来的治疗方案和最终评价相结合。
[Abstract]:Objective 1. A reliable three dimensional soft tissue analysis method was developed by using the reproducible craniofacial soft tissue markers. 2. The basic mean value of normal craniofacial three-dimensional soft tissue morphology and the basic proportion of each part were obtained in the Han nationality area of Liaoning Province, which provided the basic data for clinical medicine and forensic anthropology. Methods GE superconducting 1.5T MRI scanner was used to scan the head and neck of 100 Han nationality adults (50 female and 50 male). Inclusion criteria: healthy, normal development, no facial deformities and scars, regular arrangement of upper and lower teeth, normal shape of teeth and dental arch, coordination of craniomandibular relationship, molars of class I relationship, exclusion of facial plastic, orthodontic correction, History of surgery and contraindications for photographing MRI, aged 18 years or older. The 3D craniofacial reconstruction of scanned DICOM data was carried out by using VGStduio2.2MAX software. By adjusting the transparency and gray value and using filter and surface measurement appropriately, a clear 3D reconstruction image was obtained. In order to determine 53 mark points on craniofacial soft tissue, 10 angles of facial morphology were obtained. Then the coordinates of the mark points are obtained by WinEDMA1.0.1 software, the distance between the markers is 31 items, and 51 items of horizontal and vertical proportional indices are established. The results were statistically analyzed by SPSS17.0 software package, and t-test was carried out in two groups: male and female. Result 1. The 3D measurement of craniofacial soft tissue was realized by MRI reconstruction, including 53 markers and 92 items. The distance between the markers of craniofacial measurement was 31, the difference between men and women was statistically significant (P < 0.05), the angle measurement was 10, there were 2 (P < 0.05). There were 51 items of basic proportion relationship between craniofacial parts and 14 items of statistical significance (P < 0.05). 2. In the 3D measurement of craniofacial soft tissue, the inaccurate points mainly involve the mandibular corner, zygomatic point and several mark points of the ear. The system has high accuracy and meets the requirements of anthropometry. Conclusion 1. The three dimensional measurement system of craniofacial soft tissue based on MRI can be used as a reliable three dimensional soft tissue analysis method. 2. Three-dimensional measurement of normal craniofacial morphology of Han nationality adults in Liaoning province showed that there were obvious differences in the basic mean values between men and women, but there was no significant difference in facial proportions and angles between different parts of the population. We also need to further investigate the three-dimensional information of craniofacial soft tissue in future studies so as to facilitate the integration of 3D soft tissue diagnosis with future treatment and final evaluation.
【学位授予单位】:辽宁医学院
【学位级别】:硕士
【学位授予年份】:2014
【分类号】:R783.5

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