涎腺黏膜相关淋巴组织结外边缘区淋巴瘤伴导管内生长3例临床病理观察
发布时间：2018-11-06 11:48
【摘要】：目的探讨涎腺黏膜相关淋巴组织结外边缘区(MALT)淋巴瘤伴导管内生长的临床病理学特点。方法对3例伴导管内生长的涎腺MALT淋巴瘤的组织病理学、免疫组化结果进行分析,并复习相关文献。结果 3例具有一般MALT淋巴瘤的病理学特征,包括中心细胞样细胞、单核样B细胞,滤泡植入及淋巴上皮病变。特殊之处在于肿瘤细胞在多个扩张的导管内生长,且充满整个导管,导管内肿瘤细胞形态单一,呈单核样B细胞外观,免疫组化导管内肿瘤细胞CD20及bcl-2(+)。结论涎腺MALT淋巴瘤伴肿瘤细胞导管内生长,这种特殊的形态学特征也许对于诊断MALT淋巴瘤有一定意义,但尚需收集更多的样本来验证。
[Abstract]:Objective to investigate the clinicopathological features of (MALT) lymphoma with intraductal growth in mucosa-associated lymphoid tissue of salivary gland. Methods the histopathological and immunohistochemical results of 3 cases of salivary gland MALT lymphoma with intraductal growth were analyzed and the relevant literatures were reviewed. Results the pathological features of MALT lymphoma were found in 3 cases, including central cell-like cells, monocyte-like B cells, follicular implantation and lymphoepithelial lesions. The special feature is that the tumor cells grow in multiple dilated ducts and fill the whole ducts. The tumor cells in the ducts have a single appearance of mononuclear B cells. The tumor cells in the ducts are CD20 and bcl-2 (). By immunohistochemistry. Conclusion salivary gland MALT lymphoma with tumor cell growth in ducts may have some significance in the diagnosis of MALT lymphoma, but more samples should be collected to verify it.
【作者单位】： 首都医科大学附属北京友谊医院病理科;唐山市人民医院病理科;
【分类号】：R739.8
[Abstract]:Objective to investigate the clinicopathological features of (MALT) lymphoma with intraductal growth in mucosa-associated lymphoid tissue of salivary gland. Methods the histopathological and immunohistochemical results of 3 cases of salivary gland MALT lymphoma with intraductal growth were analyzed and the relevant literatures were reviewed. Results the pathological features of MALT lymphoma were found in 3 cases, including central cell-like cells, monocyte-like B cells, follicular implantation and lymphoepithelial lesions. The special feature is that the tumor cells grow in multiple dilated ducts and fill the whole ducts. The tumor cells in the ducts have a single appearance of mononuclear B cells. The tumor cells in the ducts are CD20 and bcl-2 (). By immunohistochemistry. Conclusion salivary gland MALT lymphoma with tumor cell growth in ducts may have some significance in the diagnosis of MALT lymphoma, but more samples should be collected to verify it.
【作者单位】： 首都医科大学附属北京友谊医院病理科;唐山市人民医院病理科;
【分类号】：R739.8
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