排龈术对楔状缺损充填修复后龈沟液中炎症因子水平的影响

发布时间：2018-11-24 11:09

【摘要】：目的通过测定龈沟液内肿瘤坏死因子-α(TNF-α)和白细胞介素-1β(IL-1β)的水平,评估排龈术对楔状缺损修复后牙周状况的影响。方法选择双侧上颌前磨牙楔状缺损患者50例,随机分为实验组和对照组,每组50颗受试牙,实验组在排龈线排龈后用3Mz350纳米复合树脂充填。对照组直接用3Mz350纳米复合树脂充填,分别在术前、术后1、3个月时进行菌斑指数、龈沟出血指数以及龈沟探诊深度等临床指标检查和龈沟液取样,对TNF-α和IL-1β水平进行测定。结果术前两组各项指标差异不具有显著性(P0.05);术后1、3个月时,两组各临床指标差异不具有显著性(P0.05),但实验组患者龈沟液TNF-α和IL-1β水平明显低于对照组(P0.05)。填充后1年随访研究发现,实验组修复体的脱落率、两组边缘不密合率均低于对照组(P0.05)。结论排龈术可以提高楔状缺损填充修复的治疗效果。
[Abstract]:Objective to evaluate the effect of gingival dissection on periodontal status after wedge-shaped defect repair by measuring the levels of tumor necrosis factor- 伪 (TNF- 伪) and interleukin-1 尾 (IL-1 尾) in gingival crevicular fluid. Methods 50 patients with wedge-shaped defects of maxillary premolars were randomly divided into experimental group and control group. The experimental group was filled with 3Mz350 nanocomposite resin after gingival retraction. The control group was filled with 3Mz350 nanocomposite resin directly. The plaque index, gingival sulcus bleeding index and probing depth of gingival crevicular fluid were examined before operation, 1 month and 3 months after operation, respectively, and gingival crevicular fluid samples were taken. The levels of TNF- 伪 and IL-1 尾 were measured. Results there was no significant difference between the two groups before operation (P0.05). At 1 and 3 months after operation, there was no significant difference in clinical indexes between the two groups (P0.05), but the levels of TNF- 伪 and IL-1 尾 in gingival crevicular fluid in the experimental group were significantly lower than those in the control group (P0.05). One year after filling, it was found that the rate of abscission of the prosthesis and the rate of edge untightness in the two groups were lower than those in the control group (P0.05). Conclusion gingival retraction can improve the therapeutic effect of wedge-shaped defect filling.
【作者单位】：重庆邮电大学医院口腔科;重庆医科大学附属第一医院口腔科;
【分类号】：R783.3

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