口腔颌面部多间隙感染的病原学分析与临床治疗

发布时间：2019-03-16 12:54

【摘要】：目的探讨口腔颌面部多间隙感染的病原菌分布及临床治疗方法,为口腔颌面部多间隙感染的治疗提供依据。方法调查2011年10月-2013年5月100例口腔颌面部多间隙感染患者临床资料,依据随机数字表法分为观察组和对照组,每组各50例;对照组患者给予常规对症治疗,观察组患者在常规对症治疗基础上行脓肿切开引流联合高压氧治疗,采用SPSS21.0进行统计分析。结果口腔颌面部多间隙感染最常见的病原菌为金黄色葡萄球菌和星座链球菌星座亚种;观察组患者中显效29例、有效19例,治疗总有效率为96.0%;对照组患者中显效9例、有效31例,治疗总有效率为80.0%;观察组患者治疗的总有效率明显比对照组高(P0.05);观察组患者治疗后白细胞计数明显比对照组低(P0.05);观察组患者发生败血症1例,术后并发症发生率为2.0%;对照组患者发生败血症3例、纵隔炎及心力衰竭各2例,术后并发症发生率为14.0%,观察组患者术后并发症发生率明显低于对照组(P0.05)。结论口腔颌面部多间隙感染的病原菌主要是金黄色葡萄球菌和星座链球菌星座亚种,常规对症治疗基础上的脓肿切开引流联合高压氧治疗具有良好的临床疗效。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria in oral and maxillofacial multi-space infection and its clinical treatment, so as to provide evidence for the treatment of oral and maxillofacial multi-space infection. Methods from October 2011 to May 2013, 100 patients with oral and maxillofacial multi-space infection were divided into observation group (n = 50) and control group (n = 50). The patients in the control group were treated with conventional symptomatic therapy. The patients in the observation group were treated with abscess incision and drainage combined with hyperbaric oxygen therapy on the basis of routine symptomatic treatment. SPSS21.0 was used for statistical analysis. Results Staphylococci aureus and Streptococcus astrococcus subspecies were the most common pathogens in oral and maxillofacial multi-space infection, in the observation group, 29 cases were effective and 19 cases were effective, the total effective rate was 96.0%. The total effective rate was 80.0% in the control group, and the total effective rate in the observation group was significantly higher than that in the control group (P0.05), and the total effective rate in the observation group was significantly higher than that in the control group (P0.05). After treatment, the leukocyte count in the observation group was significantly lower than that in the control group (P0.05), one patient in the observation group had septicemia, and the incidence of postoperative complications was 2.0%. There were 3 cases of septicemia, 2 cases of mediastinal inflammation and 2 cases of heart failure in the control group. The incidence of postoperative complications was 14.0%. The incidence of postoperative complications in the observation group was significantly lower than that in the control group (P0.05). Conclusion Staphylococcus aureus and Streptococcus astrococci are the main pathogens of multiple space infections in oral and maxillofacial regions. The conventional treatment of abscess incision and drainage on the basis of symptomatic treatment combined with hyperbaric oxygen therapy has a good clinical effect.
【作者单位】：永康市中医院口腔科;
【基金】：浙江省医药卫生基金资助项目(2011KYB033)
【分类号】：R782.3

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