103例腮腺癌的治疗疗效和预后因素分析

发布时间：2019-05-14 23:30

【摘要】：目的:分析术后辅助治疗对腮腺癌的疗效,探讨腮腺癌的预后因素。方法:回顾性分析腮腺癌患者103例,分析其生存率、预后因素、比较单纯手术和术后辅助治疗的局控率和无复发生存率、分析各因素与局控率和无复发生存率的相关性。结果:单纯手术患者和术后辅助治疗患者5年局控率、5年无复发生存率及5年生存率分别为61.90%vs.81.96%、59.52%vs.78.69%及68.50%vs.88.12%(均P0.01)。治疗方式、T分期、颈部淋巴结转移及分化程度与5年局控率和5年无复发生存率相关(均P0.01)。治疗方式、分化程度、T分期及颈部淋巴结转移与生存相关(均P0.01)。结论:术后辅助治疗能提高腮腺癌的5年局控率、5年无复发生存率及5年生存率;分化程度、T分期及颈部淋巴结转移是腮腺癌预后高危因素。
[Abstract]:Objective: to analyze the curative effect of postoperative adjuvant therapy on parotid carcinoma and to explore the prognostic factors of parotid carcinoma. Methods: 103 patients with parotid carcinoma were analyzed retrospectively. the survival rate and prognostic factors were analyzed. The local control rate and recurrence-free survival rate were compared between simple operation and postoperative adjuvant therapy. The correlation between each factor and local control rate and recurrence-free survival rate was analyzed. Results: the 5-year local control rate, 5-year recurrence-free survival rate and 5-year survival rate were 61.90% vs. 81.96%, respectively. 59.52% vs.78.69% and 68.50% vs.88.12% (all P 0.01). Treatment, T stage, cervical lymph node metastasis and differentiation were correlated with 5-year local control rate and 5-year recurrence-free survival rate (all P 0.01). Treatment, differentiation, T stage and cervical lymph node metastasis were correlated with survival (all P 0.01). Conclusion: postoperative adjuvant therapy can improve the 5-year local control rate, 5-year recurrence-free survival rate and 5-year survival rate of parotid carcinoma, and the degree of differentiation, T stage and cervical lymph node metastasis are high risk factors for prognosis of parotid carcinoma.
【作者单位】：南昌大学第一附属医院肿瘤科;
【分类号】：R739.8

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