骨质疏松老年无牙颌患者全口义齿重衬与骨转化标志物的相关性
发布时间：2019-05-19 11:48
【摘要】：背景:患有骨质疏松的老年无牙颌患者剩余牙槽嵴往往形态不佳,修复难度较大,目前尚无相应参考指标来反映此类患者剩余牙槽嵴吸收的情况和指示重衬等临床处理的频率。目的:分析患有骨质疏松的老年无牙颌患者全口义齿重衬频率与血清中骨钙素和Ⅰ型胶原羧基端交联肽两种骨转化标志物水平之间的相关性,以期为临床全口义齿修复提供参考。方法:按照纳入标准随机选取50例已行全口义齿修复并患有骨质疏松的老年无牙颌患者,对其进行相关问卷调查并查阅病史确定义齿重衬频率,同时采集患者空腹静脉血,采用电化学发光免疫法测量血清中骨钙素与Ⅰ型胶原羧基端交联肽的水平,通过Pearson相关性检验的统计学方法来分析重衬频率与骨钙素和Ⅰ型胶原羧基端交联肽之间的关系。结果与结论:患者的义齿重衬频率与血清中骨钙素水平之间有显著的正相关关系(r=0.517,P0.01),而其与血清中Ⅰ型胶原羧基端交联肽水平并未观察到显著相关性(r=0.278,P=0.0510.05),但二者有着相近的变化趋势。说明对于患有骨质疏松的老年无牙颌患者来说,检测血清中骨转化标志物水平有助于全口义齿修复疗效预后的评估和诊疗决策的制定。
[Abstract]:Background: the residual alveolar ridge in elderly edentulous patients with osteoporosis is often poor in shape and difficult to repair. At present, there are no corresponding reference indexes to reflect the absorption of residual alveolar ridge and the frequency of clinical treatment such as heavy lining. Objective: to analyze the correlation between the frequency of complete denture alignment and the level of serum osteocalcin and type I collagen carboxy terminal crosslinked peptide in elderly edentulous jaw patients with osteoporosis. In order to provide reference for clinical complete denture repair. Methods: according to the inclusion criteria, 50 elderly edentulous jaw patients who had undergone complete denture restoration and osteoporosis were randomly selected and investigated by questionnaire, and the frequency of denture heavy lining was determined by consulting the medical history. At the same time, fasting venous blood was collected. The levels of osteocalcin and type I collagen carboxy terminal crosslinked peptide in serum were measured by electrochemiluminescence immunoassay. The relationship between recontrast frequency and osteocalcin and type I collagen carboxy terminal crosslinked peptide was analyzed by Pearson correlation test. Results and conclusion: there was a significant positive correlation between the frequency of denture realignment and the level of osteocalcin in serum (r 鈮，
本文编号：2480701
[Abstract]:Background: the residual alveolar ridge in elderly edentulous patients with osteoporosis is often poor in shape and difficult to repair. At present, there are no corresponding reference indexes to reflect the absorption of residual alveolar ridge and the frequency of clinical treatment such as heavy lining. Objective: to analyze the correlation between the frequency of complete denture alignment and the level of serum osteocalcin and type I collagen carboxy terminal crosslinked peptide in elderly edentulous jaw patients with osteoporosis. In order to provide reference for clinical complete denture repair. Methods: according to the inclusion criteria, 50 elderly edentulous jaw patients who had undergone complete denture restoration and osteoporosis were randomly selected and investigated by questionnaire, and the frequency of denture heavy lining was determined by consulting the medical history. At the same time, fasting venous blood was collected. The levels of osteocalcin and type I collagen carboxy terminal crosslinked peptide in serum were measured by electrochemiluminescence immunoassay. The relationship between recontrast frequency and osteocalcin and type I collagen carboxy terminal crosslinked peptide was analyzed by Pearson correlation test. Results and conclusion: there was a significant positive correlation between the frequency of denture realignment and the level of osteocalcin in serum (r 鈮，
本文编号：2480701
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