吉林省2004年—2006年麻疹流行趋势分析

发布时间：2018-02-28 04:27

本文关键词： 麻疹流行病学监测　出处：《吉林大学》2006年硕士论文　论文类型：学位论文

【摘要】： 麻疹是一种严重威胁儿童健康的急性传染病。据世界卫生组织(WHO)估计,全球每年仍有麻疹病例约4400万,其中有100万儿童死于麻疹。在疫苗可预防的病毒性疾病中,麻疹仍是死亡例数最多的疾病。中国于1965年开始应用麻疹疫苗,特别是1978年开展计划免疫后,麻疹发病已得到有效控制。1985～2000年我国麻疹发病率每年在(5-10) /10万,但近年麻疹发病率有上升的趋势。吉林省1997～2001年平均发病率和年发病率均低于全国平均发病率水平,定为一类监测省份,重点实施消除麻疹暴发策略。本研究工作根据2004-2006年麻疹病例个案流行病学资料分析近年吉林省麻疹流行趋势,结合实验室血清学及病原学资料,揭示麻疹病毒的起源地和传播途径,科学评价疫苗免疫效果,分析麻疹流行野病毒株的基因特性和抗原性改变,为吉林省制订消除麻疹的策略和措施提供依据。
[Abstract]:Measles is an acute infectious disease that poses a serious threat to children's health. The World Health Organization estimates that there are still about 44 million measles cases in the world every year, of which 1 million children die from measles. Measles is still the most common cause of death. China began to use measles vaccine on 1965, especially after planned immunization was carried out on 1978. Measles incidence has been effectively controlled in China from 1985 to 2000. The annual measles incidence in China is 5-10) / 100,000. The average incidence and annual incidence of measles in Jilin Province from 1997 to 2001 were lower than the national average incidence rate. Based on the epidemiological data of measles cases from 2004 to 2006, this study analyzed the epidemic trend of measles in Jilin Province in recent years, combined with laboratory serological and etiological data to reveal the origin and transmission of measles virus. To evaluate the immune effect of the vaccine scientifically, to analyze the genetic characteristics and antigenicity of wild measles virus strains, and to provide the basis for the strategies and measures to eliminate measles in Jilin province.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2006
【分类号】：R511.1;R181.8

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