南京市2006-2015年流感流行病学特征分析

发布时间：2018-03-11 08:18

本文选题：流感　切入点：人　出处：《中华疾病控制杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的分析2006-2015年南京市流行性感冒(简称流感)流行病学特征,为流感防控提供依据。方法在中国疾病预防控制中心信息系统下载流感样病例(influenza like illness,ILI)监测、流感暴发疫情监测和病原学监测资料,应用SPSS 16.0软件进行数据分析。结果 2006-2015年ILI数和流感样病例百分比(ILI%)平均分别为5 823例和5.0%,ILI 5岁以下组所占比例最高(64.8%),60岁及以上年龄组所占比例最低(2.1%);2006-2015年南京市共分离检测流ILI标本31 644例,阳性病例4 762例,阳性率15.0%,不同年份、不同年龄段之间核酸检测阳性率差异均有统计学意义(均有P0.05);阳性标本中季节性H3N2 1 944例(40.8%),其次是B型流感1 374例(28.9%),甲型H1N1次之1 243例(26.1%),季节性H1N1最少201例(4.2%);不同年龄段人群流感分型构成差异有统计学意义(X~2=317.19,P0.001)。结论 ILI主要分布在5岁以下儿童,2006-2015年流感各亚型交替成为优势毒株,不同年龄段感染主要亚型不同。
[Abstract]:Objective to analyze the epidemiological characteristics of influenza in Nanjing from 2006 to 2015, and to provide evidence for influenza prevention and control. Methods Influenza was monitored in the information system of China Center for Disease Control and Prevention (CDC). Surveillance and etiological surveillance of influenza outbreaks, Results the average number of ILI cases and the percentage of influenza-like cases between 2006 and 2015 were 5 823 and 5.0% respectively. A total of 31 644 ILI specimens were isolated and detected. There were 4762 positive cases, the positive rate was 15.0%, in different years, The positive rate of nucleic acid detection was significantly different among different age groups (all P 0.05A, P 0.05), positive samples of seasonal H3N2 1 944 cases were 40.8%, B influenza 1 374 cases were 28. 9%, A (H1N1) 1 243 cases were 26. 1% and seasonal H1N1 were at least 201 cases with 4. 2%. There were significant differences in influenza typing composition among the same age groups. Conclusion ILI mainly distributes in children under 5 years of age and the subtypes of influenza alternately become dominant strains from 2006 to 2015. The main subtypes of infection are different in different age groups.
【作者单位】：南京市疾病预防控制中心急性传染病防制与学校卫生科;东南大学公共卫生学院流行病与卫生统计学教研室;
【基金】：国家自然科学基金(81273143) 江苏省重点研发计划(社会发展)项目(BE2015679) 江苏省“六大人才高峰”第十一批高层次人才选拔培养资助项目(2014-WSN-40)
【分类号】：R181.3;R511.7

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